The effects of patient–centered pharmaceutical care intervention among uncontrolled hypertensive patients in communities

Authors

  • Ongart Maneemai School of Pharmaceutical Sciences, University of Phayao
  • Khemanat Ratworawong School of Pharmaceutical Sciences, University of Phayao
  • Phitchayut Rattanatanyapat University of Phayao Hospital, School of Medicine, University of Phayao
  • Kunwara Ob-un Chiang Rai Prachanukroh Hospital
  • Chareeya Likhitwatthanakij School of Pharmaceutical Sciences, University of Phayao
  • Nattapat Sornjumpa School of Pharmaceutical Sciences, University of Phayao
  • Pacharaphan Wisetsing School of Pharmaceutical Sciences, University of Phayao
  • Thanvakorn Butsarn School of Pharmaceutical Sciences, University of Phayao

Keywords:

Hypertension, Patient – Centered Care, Pharmaceutical Care, Pharmacist

Abstract

This randomized control trail aimed to evaluate the effects of the patient-centered pharmaceutical care (PCPC) intervention among the uncontrolled hypertensive patients. The participants were uncontrolled hypertensive patients, selected from four health–promoting hospitals in Muang Phayao district, Phayao province, Thailand. Eligible patients were recruited and randomly assigned, by the hospital, to either PCPC (n = 36) or usual care (UC) group (n = 33). The PCPC group was provided with three PCPC interventions at home and one telemonitoring by a clinical pharmacist. Primary outcomes were systolic (SBP) and diastolic blood pressure (DBP). Secondary outcomes were patients’ knowledge; self– care behaviors; medication adherence and quality of life (QOL). The outcomes were measured at baseline, sixth and twelfth week of the study. At the first evaluation, the results indicated that knowledge and self-care behaviors in the PCPC group were significantly higher than those of the UC group. At the end of the study, the SBP of PCPC group was lower than that of the UC group significantly. According to the PCPC group, patients’ knowledge and self-care behaviors were improved significantly compared to the UC group. Medication adherence and QOL were not significantly differences. In conclusion, the PCPC intervention was an effective intervention for uncontrol hypertensive patients and it improved patients’ SBP, knowledge and self-care behaviors.

References

Thonghong A, Thepsitha K and Jongpiriyaanun P. Chronic diseases surveillance report 2012 [document on the Internet]. Nonthaburi: Bureau of Epidemiology, Department of Disease Control, Ministry of Public Health; 2012 [updated 2014 January 9; cited 2019 January 9]. Available from: http://www.boe.moph.go.th/report.php?cat=12.

Wolf-Maier K, Cooper RS, Kramer H, Banegas JR, Giampaoli S, Joffres MR, et al. Hypertension treatment and control in five European countries, Canada, and the United State. Hypertension. 2004;43:10-17.

James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA. 2014;311(5):507-20.

Psaty BM, Smith NL, Siscovick DS, Koepsell TD, Weiss NS, Heckbert SR, et al. Health outcomes associated with antihypertensive therapies used as first-line agents. A systematic review and meta-analysis. JAMA. 1997;277(9):739-45.

Bechel DL, Myers WA, Smith DG. Does patient-centered care pay off?. Jt Comm J Qual Improv. 2000;26(7):400‐9.

Robinson JH, Callister LC, Berry JA, Dearing KA. Patient-centered care and adherences: definitions and application to improve outcomes. J Am Acad Nurse Prac. 2008(20):6000-7.

Hathirat S. Family medicine handbook. 3rd ed. Bangkok: Moh-Chao-Ban Publishing House; 2008.

Kuntz JL, Safford MM, Singh JA, Phansalkar S, Slight SP, Her QL, et al. Patient-centered interventions to improve medication management and adherence: a qualitative review of research findings. Patient Educ Couns. 2014;97(3):310-26.

Zillich AJ, Jaynes HA, Bex SD, Boldt AS, Walston CM, Ramsey DC, et al. Evaluation of pharmacist care for hypertension in the Veterans Affairs patient-centered medical home: a retrospective case-control study. Am J Med. 2015;128(5):539.e1-6.

Sweet MG. A patient-centered approach to chronic disease management. JAAPA. 2004;17(11):25‐28.

Manadee C, Ploylearmsang C and Sookaneknun P. Effects of elderly care with chronic diseases on quality use of medicine at home in area of sub-district health promoting hospitals, Somdet district, Kalasin province. Isan J Pharm Sci. 2014;10(3):354-71.

Laloon P, Madhyamankura N, and Malarat A. Self-care behavior of hypertensive patients at out-patient department of HRH Princess Maha Chaki Sirindhorn medical center. J Med Health Sci. 2011;18(3):160-9.

Morisky DE, Ang A, Krousel-Wood M, Ward HJ. Predictive validity of a medication adherence measure in an outpatient setting. J Clin Hypertens (Greenwish). 2008;10(5): 348-54.

Pattanaphesaj J, Thavorncharoensap M. Measurement properties of the EQ-5D-5L compared to EQ-5D-3L in the Thai diabetes patients. Health Qual Life Outcomes. 2015 Feb 6;13:14. doi: 10.1186/s12955-014-0203-3. PMID: 25890017; PMCID: PMC4328309.

Zhao PX, Wang C, Qin L, Yuan M, Xiao Q, Guo YH, et al. Effect of clinical pharmacist’s pharmaceutical care intervention to control hypertensive outpatients in China. Afr J Pharm Pharmacol. 2012;6(1):48-56.

Taylor BC, Wilt TJ and Welch HG. Impact of diastolic and systolic blood pressure on mortality: implications for the definition of “normal”. J Gen Int Med. 2011;26(7):685.

Staessen JA, Gasowski J, Wang JG, Thijs L, Hond ED. Boissel JP, et al. Risk of untreated and treated isolated systolic hypertension in the elderly: meta-analysis of outcome trials. Lancet. 2000;355:865-72.

Kannel WB. Elevated systolic blood pressure as a cardiovascular risk factor. Am J Cardiology. 2000;321:412-9.

Tobari H, Arimoto T, Shimojo N, Yuhara K, Noda H, Yamagishi K, et al. Physician–pharmacist cooperation program for blood pressure control in patients with hypertension: a randomized-controlled trial. Am J Hypertens. 2010;23(10):1144-52.

Morgado M, Rolo S, and Castelo-Branco M. Pharmacist intervention program to enhance hypertension control: a randomised controlled trial. Int J Clin Pharm. 2011;1(33):132-40.

Saleem F, Hassali MA, Shafie AA, Ul Haq N, Farooqui M, Aljadhay H, et al. Pharmacist intervention in improving hypertension-related knowledge, treatment medication adherence and health-related quality of life: a non-clinical randomized controlled trial. Health Expect. 2015;18(5):1270-81.

Sookaneknun P, Richards RM, Sanguansermsri J, Teerasut C. Pharmacist involvement in primary care improves hypertensive patient clinical outcomes. Ann Pharmacother. 2004;38(12):2023‐2028.

Hunt JS, Siemienczuk J, Pape G, Rozenfeld Y, MacKay J, LeBlanc BH, Touchette D. A randomized controlled trial of team-based care: impact of physician-pharmacist collaboration on uncontrolled hypertension. J Gen Intern Med. 200;23(12):1966-72.

Mehos BM, Saseen JJ, MacLaughlin EJ. Effect of pharmacist intervention and initiation of home blood pressure monitoring in patients with uncontrolled hypertension. Pharmacotherapy. 2000;20(11):1384‐89.

Roumie CL, Elasy TA, Greevy R, Griffin MR, Liu X, Stone WJ, et al. Improving blood pressure control through provider education, provider alerts, and patient education: a cluster randomized trial. Ann Intern Med. 2006;145 (3):165-75.

Carter BL, Bergus GR, Dawson JD, Farris KB, Doucette WR, Chrischilles EA, et al. A cluster randomized trial to evaluate physician/pharmacist collaboration to improve blood pressure control. J Clin Hypertens (Greenwich). 2008;10(4):260-71.

Li W, Liu L, Puente JG, Li Y, Jiang X, Jin S, et al. Hypertension and health-related quality of life: an epidemiological study in patients attending hospital clinics in China. J Hypertens. 2005;23(9):1667-76.

Gusmão JL, Mion D Jr, Pierin AM. Health-related quality of life and blood pressure control in hypertensive patients with and without complications. Clinics (Sao Paulo). 2009;64(7):619‐628.

Akhtar, M. M., Waheed, A., Sheikh, D. and Hussain, A. Role of pharmacist in improving health related quality of life (HRQoL) in hypertensive patients in Pakistan. Am J Pharmaco Sci. 2014;5(2B):17-22.

Taichman DB, Shin J, Hud L, Archer-Chicko C, Kaplan S, Sager JS, et al. Health-related quality of life in patients with pulmonary arterial hypertension. Respir Res. 2005;6(1):92. doi: 10.1186/1465-9921-6-92.

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Published

2022-04-30

How to Cite

1.
Maneemai O, Ratworawong K, Rattanatanyapat P, Ob-un K, Likhitwatthanakij C, Sornjumpa N, Wisetsing P, Butsarn T. The effects of patient–centered pharmaceutical care intervention among uncontrolled hypertensive patients in communities. Health Sci Tech Rev [Internet]. 2022 Apr. 30 [cited 2024 Nov. 19];15(1):23-3. Available from: https://li01.tci-thaijo.org/index.php/journalup/article/view/249479

Issue

Vol. 15 No. 1 (2022): January - May

Section

Research articles

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