Free radical scavenging capacity and modulative effect on antioxidant enzyme activity of Pluchea indica Less. tea leaf extract

Authors

  • Naruemon Thoobbucha Faculty of Science, Burapha University, Chonburi Province 20131
  • Chatchawin Petchler Department of Biochemistry, Faculty of Science, Burapha University, Chonburi Province 20131

Keywords:

Pluchea indica Less. tea leaf extract, free radical scavenging, antioxidant enzyme

Abstract

The aim of the present study is to investigate the free radical scavenging and modulative effect on the antioxidant enzyme activity of Pluchea indica Less. tea leaf extract. Superoxide and hydroxyl radical scavenging activities were measured. The result showed that the percentage of free radical inhibition markedly increased both on superoxide and hydroxyl radicals in concentration-dependent manners. IC50 levels against superoxide and hydroxyl radicals were 265.84 ± 20.55 μg/mL, and 161.91 ± 4.94 μg/mL, respectively. Moreover, the activities of 1 unit/mL of catalase (CAT) and glutathione peroxidase (GPx) were assayed with different concentrations of the extract for 30 minute incubation. The increase of catalase activity in a concentration-dependent profile was observed but it did not alter in case of glutathione peroxidase activity.
vol8No2

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Published

2015-06-21

How to Cite

1.
Thoobbucha N, Petchler C. Free radical scavenging capacity and modulative effect on antioxidant enzyme activity of Pluchea indica Less. tea leaf extract. Health Sci Tech Rev [Internet]. 2015 Jun. 21 [cited 2024 Dec. 31];8(2):74-9. Available from: https://li01.tci-thaijo.org/index.php/journalup/article/view/42599

Issue

Vol. 8 No. 2 (2015): May - August

Section

Research articles

License

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