Cytotoxicity evaluation of leaf-extract from Moringa oleifera, Cratoxylum formosum, and Mangifera indica

Authors

  • Ratsada Praphasawat
  • Maitree Suttajit
  • Suphachai Charoensin
  • Rungthip Thongbuntho
  • Paween Kunsorn
  • Kwanchaya Jeerawut
  • Pramote Vanittanakom

Keywords:

Cytotoxicity test, WST-1 assay, Moringa oleifera, Cratoxylum formosum, Mangifera indica, TK6 cells

Abstract

The study is set out to investigate the cytotoxic effect of three water leaf-extract from indigenous plants: Moringa oleifera (MO), Cratoxylum formosum (CF), and Mangifera indica (MI), using TK6 human lymphoblastoid cells (TK6 cell) as a model. The leaf-extract of CF showed the lowest toxicity among all extracts while the MI leaf-extracts showed the highest toxicity to TK6 cells. The half maximum inhibitory concentration (IC50) of CF, MO, and MI were 381.48 ± 36.13, 198.21 ± 7.41, and 142 ± 22.87 μg/mL. The result suggested that water extracts of CF, MO, and MI have low cytotoxicity towards TK6 cells.

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Published

2016-08-24

How to Cite

1.
Praphasawat R, Suttajit M, Charoensin S, Thongbuntho R, Kunsorn P, Jeerawut K, Vanittanakom P. Cytotoxicity evaluation of leaf-extract from Moringa oleifera, Cratoxylum formosum, and Mangifera indica. Health Sci Tech Rev [Internet]. 2016 Aug. 24 [cited 2024 Apr. 25];9(2):5-8. Available from: https://li01.tci-thaijo.org/index.php/journalup/article/view/65358

Issue

Section

Research articles