Cynometra cauliflora Flower Extract on Antibacterial and Antioxidant Activity
Keywords:
MRSA 142, Cynometra cauliflora, Antibacterial, Antioxidant, Phenolic compoundAbstract
Nowadays, vegetables, fruits, and local herbs are popular for testing their antimicrobial and antioxidant properties. The purpose of this research was to study the effect of Cynometra cauliflora (C. cauliflora) flower extract on antibacterial and antioxidant activities. Agar well diffusion method, DPPH assay, and Folin-Ciocalteu method were used to determine the antibacterial activity, to study the antioxidant property, and to identify phenolic quantification, respectively. The results of this study showed that the extract of C. cauliflora flower has antibacterial effect against Staphylococcus aureus, Micrococcus luteus and Methicilin-Resistant Staphylococcus aureus with the inhibitory sites were 21.00±0.17, 25.00±0.00 and 26.00±0.15 mm, respectively. Minimum inhibitory concentration and minimum bactericidal concentration were 18.75 mg/mL and 300.00 mg/mL, respectively. In addition, the C. cauliflora flower extract showed anti-oxidant activity with an IC50 value was 0.11 μg/mL, while vitamin C had an IC50 of 312.62 μg/mL. This study also demonstrated that C. cauliflora flower extract contains 4.45 μg GAE/g fresh weight of total phenolic compounds.
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