Intermittent Fasting for Weight Loss and Lower Blood Sugar Levels in Patients with Type 2 Diabetes Mellitus
Keywords:
Intermittent fasting, Type 2 diabetes, Weight loss, Blood sugar levelAbstract
Type 2 Diabetes Mellitus (DM) is the most prevalent (occurring in 90% of cases) out of all types of DM. Insulin resistance is a cause of DM. Normally, when we consume food, the pancreas will release insulin to transport the food's sugar into the cell for use as fuel. As a result of insulin resistance, elevated blood sugar levels or DM develop. The body's inability to efficiently control blood sugar due to insulin resistance results in consistently high blood sugar. It may result in uncontrolled DM and increase the risk of serious complications including cardiovascular disease, renal disease, retinopathy, and neuropathy. The common infections observed by high blood sugar, including gastrointestinal, fungal, and skin infections. Controlling blood sugar is essential for preventing complications from type 2 DM.
Intermittent fasting is highly intriguing and has a lot of evidence to support its advantages. It offers health benefits in terms of weight loss and blood sugar control in those with type 2 diabetes. In this article, the method, efficiency, and safety of utilizing intermittent fasting to reduce body weight and regulate blood sugar in people with type 2 diabetes were examined. The information covered the definition, principles and mechanisms, types, benefits and effects, how to plan and start, how to overcome obstacles, how to measure and evaluate, and how to apply intermittent fasting to patients with diabetes.
References
Anne Helmenstine. (2022). Gluconeogenesis Pathway and Definition. Retrieved July 26, 2023, from https://sciencenotes.org/gluconeogenesis-pathway-and-definition/#google_vignette.
Anton, S. D., Moehl, K., Donahoo, W. T., Marosi, K., Lee, S. A., Mainous, A. G., ... & Mattson, M. P. (2018). Flipping the metabolic switch: Understanding and applying the health benefits of fasting. Obesity, 26(2), 254-268.
Antoni, R., Johnston, K.L., Collins, A.L., & Robertson, M.D. (2017). Effects of intermittent fasting on glucose and lipid metabolism. Proceedings of the Nutrition Society, 77(3), 275-286.
Barnosky, A. R., Hoddy, K. K., Unterman, T. G., & Varady, K. A. (2014). Intermittent fasting vs daily calorie restriction for type 2 diabetes prevention: a review of human findings. Translational Research, 164(4), 302-311.
Byrne, N.M., Sainsbury, A., King, N.A., Hills, A.P. & Wood R.E., (2018). Intermittent energy restriction improves weight loss efficiency in obese men: the MATADOR study. International Journal of Obesity. 42(2), 129-38.
Carter, S., Clifton, P.M., & Keogh, J.B. (2018). Effect of Intermittent Compared with Continuous Energy Restricted Diet on Glycemic Control in Patients with Type 2 Diabetes: A Randomized Noninferiority Trial. JAMA Network Open. 1(3), e180756
Catenacci, V. A., Pan, Z., Ostendorf, D., Brannon, S., Gozansky, W. S., Mattson, M. P., ... Melanson, E. L. (2016). A randomized pilot study comparing zero-calorie alternate-day fasting to daily caloric restriction in adults with obesity. Obesity, 24(9), 1874-1883.
Furmli, S., Elmasry, R., Ramos, M., & Fung, J. (2018). Therapeutic use of intermittent fasting for people with type 2 diabetes as an alternative to insulin. BMJ Case Report. 9, bcr2017221854.
Harris, L., Hamilton, S., Azevedo, L. B., Olajide, J., De Brún, C., Waller, G., ... Summerbell, C. (2018). Intermittent fasting interventions for treatment of overweight and obesity in adults: a systematic review and meta-analysis. JBI Database of Systematic Reviews and Implementation Reports, 16(2), 507-547.
Horne, B. D., Muhlestein, J. B., Anderson, J. L., & Health, I. (2015). Health effects of intermittent fasting: hormesis or harm? A systematic review. The American Journal of Clinical Nutrition, 102(2), 464-470.
Jensen, M. D., Ryan, D. H., Apovian, C. M., Ard, J. D., Comuzzie, A. G., Donato, K. A., ... Yanovski, S. Z. (2014). 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. Circulation, 129(25 Suppl 2), S102-38.
Leanne, H., Sharon, H., Liane, B. A., Joan, O., Caroline, D. B., Gillian, W., … Louisa, E. (2018). Intermittent fasting interventions for treatment of overweight and obesity in adults: a systematic review and meta-analysis. JBI Database of Systematic Reviews and Implementation Reports. 16(2), 507-547.
Joaquim, L., Faria, A., Loureiro, H., & Matafome, P. (2022). Benefits, mechanisms, and risks of intermittent fasting in metabolic syndrome and type 2 diabetes. Journal of Physiology and Biochemistry. 78, 295-305.
Mattson, M. P., Longo, V. D., & Harvie, M. (2017). Impact of intermittent fasting on health and disease processes. Ageing Research Reviews, 39, 46-58.
Moro, T., Tinsley, G., Bianco, A., Marcolin, G., Pacelli, Q. F., Battaglia, G., … Paoli, A. (2016). Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males. Journal of translational medicine, 14(1), 1-10.
Patterson, R. E., & Sears, D. D. (2017). Metabolic effects of intermittent fasting. Annual Review of Nutrition, 37, 371-393.
Patterson, R. E., Laughlin, G. A., LaCroix, A. Z., Hartman, S. J., Natarajan, L., Senger, C. M., ... Gallo, L. C. (2015). Intermittent fasting and human metabolic health. Journal of the Academy of Nutrition and Dietetics, 115(8), 1203-1212.
Patterson, R. E., Sears, D. D., & Metformin, A. M. (2017). Intermittent fasting and human metabolic health. Journal of the Academy of Nutrition and Dietetics, 117(9), 1375-1383.
Rui, L. (2014). Energy metabolism in the liver. Comprehensive Physiology, 4(1), 177-197.
Supata, P., Aungwattana, S., & Tamdee, D. (2020). Effects of Buddhist-based Weight Loss Program on Weight Loss Practices and Bodywieght Among Overweight Novice Monks. Nursing Journal CMU, 47(3), 288-299
Sutton, F.E., Beyl, R., Early, S.K., Cefalu, T.W., Tavussin, E., & Peterson, M.C. (2018). Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidatives Stress Even Whiteout weight Loss in Men with Prediabetes, Cell Metabolism, 27(6), 1212-1221
The Royal College of family Physicians of Thailand. (2022). Guidelines for caring for type 2 diabetic patients into diabetes remission through rigorous behavior modification for medical and public health personnel, 1-11
Tinsley, G. M., & La Bounty, P. M. (2015). Effects of intermittent fasting on body composition and clinical health markers in humans. Nutrition Reviews, 73(10), 661-674.
Tinsley, G.M., Forsse, J.S., Butler, N.S., Paoli, A., Bane, A.A., & Bounty, P.M.L., (2016). Time-restricted feeding in young men performing resistance training: A randomized controlled. European Journal of Sport Science. 17(2), 200-207.
Wei, M., Brandhorst, S., Shelehchi, M., Mirzaei, H., Cheng, W. C., Budniak, …. Longo, V. D. (2017). Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease. Science Translational Medicine, 9(377), eaai8700
Wing, R.R., Lang, W., Wadden, A.T., Safford, M., Knowler, C.W., Bertoni, G.A., … Wagenknecht, L. (2011). Benefits of Modest weight loss in improving cardiovascular risk factors in overweight and obese individuals with type 2 diabetes, Diabetes Care, 34(7), 1481-1486.
Zoungas, S., Arima, H., Gerstein, C.H., Holman, R.R., Woodward, M., Reaven, P., … Chalmers, J. (2017). Effects of intensive glucose control on microvascular outcomes in patients with type 2 diabetes: a mata analysis of individual participant data from randomized controlled trials, Lancet Diabetes Endocrinal, 5(6), 431-437.
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