Effect of L-carnitine supplementation on hematology and blood chemistry in fighting bulls
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Abstract
The purpose of this study was to evaluate the effects of oral L-carnitine supplementation on alterations in a complete blood cell and blood chemistry profiles. In this study, sixteen fighting bull aged 3-5 years were divided into two experimental groups: 1) LC group (n = 8) receiving 500 mg of L-carnitine per head per day and 2) control group (n = 8) receiving placebo. There is a trial period of 8 weeks. Blood samples were analyzed for a complete blood count, and serum samples were analyzed for clinical chemistry profiles using automated blood and clinical chemistry analyzer. The results revealed that the hemoglobin and granulocyte count in the L-carnitine group was significantly higher than the control group (p < 0.05). The percentage of leukocyte in the L-carnitine group was lower than the control group (p < 0.05). There was no significant difference among the groups with regard to RBC, MCHC, MCH, MCV, hematocrit, WBCs and monocytes as well as clinical chemistry profiles. This study suggests that oral L-carnitine supplementation could influence hemoglobin production results in oxygen affinity and it also affects the immune system by stimulating granulocyte white blood cells, which is involved in the inflammatory process. Moreover, L-carnitine does not cause adverse effect due to stable blood metabolites related to liver and kidney functions, therefore it can be used as a nutrient supplement for the fighting bull.
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