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Active learning is a teaching approach which students engage in the learning process. It can increase student's motivation and knowledge. This study was aimed to assess learning outcomes and student perceptions after various activities were applied to support active learning approach in "Medicines with special administration" class of the pharmacy practice course. Instructor created various activities such as effective questioning, demonstration, and discussions of real-life problems to promote active learning. The learning outcome was assessed from paper examination. Student perceptions were self-assessed by data collecting forms. The study was carried out with 174 students who registered to pharmacy practice course. There were 133 students (76.44%) who achieved the learning outcome. Students perceived that the teaching approach was active learning with the average score of 9.05±0.80 (with a scaling of 1 to 10). Students agreed that instructor encouraged students to think and solve problems, and also illustrated important issues with the average score of 4.48±0.60 (with a scaling of 1 to 5). The barrier of this active learning approach was that the amount of content did not correspond with the limited time. It can be concluded that the course learning outcome was achieved from this active learning approach practically the same as from traditional lecture of other topics. This approach may be used to improve active learning in the pharmacy education in the future.
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