Factors influencing the properties of zein nanoparticles encapsulated with fragrances prepared by liquid-liquid dispersion

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Usaraphan Pithanthanakul
Vilai Rungsardthong
Bang-On Kiatthanakorn
Savitri Vatanyoopaisarn
Benjawan Thumthanaruk
Dudsadee Uttapap
Yulong Ding

Abstract

The duration of the fragrance is one of the factors that influences a customer’s choice of fabric softeners. Fragrances, a mixture of various aromatic compounds, usually present low solubility and stability in the environment, so they do not last long. Micro/nanoencapsulation technology of fragrances can be used to solve this problem. This research studied the factors influencing the preparation of zein nanoencapsulation with fragrances. Fruity fragrances were encapsulated in zein nanoparticles (PF-ZNs) by the liquid-liquid dispersion method, using Tween 20 as a surfactant. The effects of zein and ethanol concentrations of 0.4%–0.8% and 70%–85%, respectively, homogenized at 15,000 rpm for 5–15 min on zein encapsulation, were investigated. The fruity fragrance was loaded at 30% of the zein content. Increased zein concentration resulted in increased particle size with decreased zeta potential. Particle agglomeration was detected when the ethanol concentration was decreased from 85% to 75%. Compared to using a vacuum concentrator centrifuge, the zein nanoparticles agglomerated less when freeze-dried. The encapsulation efficiency of the fruity fragrance was 39.7%–68.4%, and the yield percentage was 54.5%–72.3% when freeze-drying was used.

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How to Cite
Pithanthanakul, U., Rungsardthong, V., Kiatthanakorn, B.-O., Vatanyoopaisarn, S., Thumthanaruk, B., Uttapap, D., & Ding, Y. (2024). Factors influencing the properties of zein nanoparticles encapsulated with fragrances prepared by liquid-liquid dispersion. Science, Engineering and Health Studies, 18, 24030001. https://doi.org/10.69598/sehs.18.24030001
Section
Biological sciences

References

Alargova, R. G., Paunov, V. N., and Velev, O. D. (2006). Formation of polymer microrods in shear flow by emulsification - solvent attrition mechanism. Langmuir, 22(2), 765–774.

Anarjan, N., Jafarizadeh-Malmiri, H., Nehdi, I. A., Sbihi, H. M., Al-Resayes, S. I., and Tan, C. P. (2015). Effects of homogenization process parameters on physicochemical properties of astaxanthin nanodispersions prepared using a solvent-diffusion technique. International Journal of Nanomedicine, 10(1), 1109–1118.

Anderson, T. J., and Lamsal, B. P. (2011). Review: Zein extraction from corn, corn products, and coproducts and modifications for various applications: A review. Cereal Chemistry, 88(2), 159–173.

Ban, Z., Zhang, J., Li, L., Luo, Z., Wang, Y., Yuan, Q., Zhou, B., and Liu, H. (2020). Ginger essential oil-based microencapsulation as an efficient delivery system for the improvement of Jujube (Ziziphus jujuba Mill.) fruit quality. Food Chemistry, 306, 125628.

Chulurks, S., Jitapunkul, K., Katanyutanon, S., Toochinda, P., and Lawtrakul, L. (2021), Stability enhancement and skin permeation application of nicotine by forming inclusion complex with β-cyclodextrin and methyl-β-cyclodextrin. Scientia Pharmaceutica, 89(4), 43.

Correia, P., Leitão, A., and Beirão-da-Costa, M. L. (2009). The effect of drying temperatures on morphological and chemical properties of dried chestnuts flours. Journal of Food Engineering, 90(3), 325–332.

Elzoghby, A. O. (2015). Protein and peptide nanoparticles for drug delivery. In Advances in Protein Chemistry and Structural Biology (Vol. 98) (Donev, R., Ed.), pp. 169-221. Cambridge: Academic Press.

Ghayempour, S., and Montazer, M. (2016). Micro/nanoencapsulation of essential oils and fragrances: Focus on perfumed, antimicrobial, mosquito-repellent and medical textiles. Journal of Microencapsulation, 33(6), 497–510.

Global Market Insights. (2023). Corn fiber market size competitive market share & forecast, 2023 – 2032. ASDReports premium market research. [Online URL: https://www.asdreports.com/market-research-report-616711/corn-fiber-market-size-competitive-market-share-forecast] accessed on May 31, 2023.

Guo, X., Ren, C., Zhang, Y., Cui, H., and Shi, C. (2020). Stability of zein‐based films and their mechanism of change during storage at different temperatures and relative humidity. Journal of Food Processing and Preservation, 44(9), e14671.

He, L., Hu, J., and Deng, W. (2018). Preparation and application of flavor and fragrance capsules. Polymer Chemistry, 9(40), 4926–4946.

Honary, S., and Zahir, F. (2013). Effect of zeta potential on the properties of nano-drug delivery systems-a review (part 2). Tropical Journal of Pharmaceutical Research, 12(2), 265–273.

Hosseini, F., Miri, M. A., Najafi, M., Soleimanifard, S., and Aran, M. (2021). Encapsulation of rosemary essential oil in zein by electrospinning technique. Journal of Food Science, 86(9), 4070–4086.

Irudayam, M. J., and Malathi, R. (2005). Methylxanthines binding with yeast total RNA in the presence of Mg2+: A speed vac-centrifugation-facilitated solid-state Fourier transform infrared analysis. Analytical Biochemistry, 339(1), 179–181.

Lee, H., Choi, C.-H., Abbaspourrad, A., Wesner, C., Caggioni, M., Zhu, T., and Weitz, D. A. (2016). Encapsulation and enhanced retention of fragrance in polymer microcapsules. ACS Applied Materials & Interfaces, 8(6), 4007–4013.

Lepock, J. R., Frey, H. E., and Ritchie, K. P. (1993). Protein denaturation in intact hepatocytes and isolated cellular organelles during heat shock. Journal of Cell Biology, 122(6), 1267–1276.

Li, F., Chen, Y., Liu, S., Qi, J., Wang, W., Wang, C., Zhong, R., Chen, Z., Li, X., Guan, Y., Kong, W., and Zhang, Y. (2017). Size-controlled fabrication of zein nano/microparticles by modified anti-solvent precipitation with/without sodium caseinate. International Journal of Nanomedicine, 12, 8197–8209.

Liu, X., Huang, L., Chen, H., Qian, M. C., and Ji, H. (2020). Pore size matching up: A novel insight into cotton textile aromatic finishing. Flavour and Fragrance Journal, 35(2), 149–156.

Lopes, S., Afonso, C., Fernandes, I., Barreiro, M.-F., Costa, P., and Rodrigues, A. E. (2019). Chitosan-cellulose particles as delivery vehicles for limonene fragrance. Industrial Crops and Products, 139, 111407.

Manayi, A., and Saeidnia, S. (2014). Cosmetics and personal care products. In Encyclopedia of Toxicology (Wexler, P., Ed.), 3rd, pp. 1043–1049. Amsterdam: Elsevier.

Namira, Z. R., Paramita, V., and Kusumayanti, H. (2021). The effect of rotational speed of homogenization on emulsion results obtained using soy lecithin emulsifier. Journal of Vocational Studies on Applied Research, 3(1), 14–17.

Parris, N., Cooke, P. H., and Hicks, K. B. (2005). Encapsulation of essential oils in zein nanospherical particles. Journal of Agricultural and Food Chemistry, 53(12), 4788–4792.

Pascoli, M., de Lima, R., and Fraceto, L. F. (2018). Zein nanoparticles and strategies to improve colloidal stability: A mini-review. Frontiers in Chemistry, 6, 6.

Pateiro, M., Gómez, B., Munekata, P. E. S., Barba, F. J., Putnik, P., Kovačević, D. B., and Lorenzo, J. M. (2021). Nanoencapsulation of promising bioactive compounds to improve their absorption, stability, functionality and the appearance of the final food products. Molecules, 26(6), 1547.

Pithanthanakul, U., Rungsardthong, V., Kiatthanakorn, B.-O., Vatanyoopaisarn, S., Thumthanaruk, B., Chaiyasat, A., Uttapap, D., and Ding, Y. (2023). Visible light-based polymerization of poly (methyl methacrylate) encapsulated fragrances used for fabric softener applications. Industrial Crops and Products, 194, 116329.

Pithanthanakul, U., Vatanyoopaisarn, S., Thumthanaruk, B., Puttanlek, C., Uttapap, D., Kietthanakorn, B., and Rungsardthong, V. (2021). Encapsulation of fragrances in zein nanoparticles and use as fabric softener for textile application. Flavour and Fragrance Journal, 36(3), 365–373.

Podaralla, S., and Perumal, O. (2012). Influence of formulation factors on the preparation of zein nanoparticles. AAPS PharmSciTech, 13(3), 919–927.

Rodsuwan, U., Pithanthanakul, U., Thisayakorn, K., Uttapap, D., Boonpisuttinant, K., Vatanyoopaisarn, S., Thumthanaruk, B., and Rungsardthong, V. (2021). Preparation and characterization of gamma oryzanol loaded zein nanoparticles and its improved stability. Food Science & Nutrition, 9(2), 616–624.

Rungsardthong, V., Pithanthanakul, U., Puttanlek, C., Uttapap, D., and Boonpisuttinant, K. (2021). Preparation of puerarin-loaded zein nanoparticles: Characterization and stability study. Journal of Current Science and Technology, 11(1), 6070.

Schneider, C. A., Rasband, W. S., and Eliceiri, K. W. (2012). NIH Image to ImageJ: 25 years of image analysis. Nature Methods, 9(7), 671–675.

Šumiga, B., Šumiga, B., Ravnjak, D., and Podgornik, B. B. (2019). Antimicrobial paper coatings containing microencapsulated Cymbopogon citratus oil. Coatings, 9(8), 470.

Suwannasang, S., Thumthanaruk, B., Zhong, Q., Uttapap, D., Puttanlek, C., Vatanyoopaisarn, S., and Rungsardthong, V. (2021). The improved properties of zein encapsulating and stabilizing sacha inchi oil by surfactant combination of lecithin and tween 80. Food and Bioprocess Technology, 14(11), 2078–2090.

Tang, Y., Zhou, Y., Lan, X., Huang, D., Luo, T., Ji, J., Mafang, Z., Miao, X., Wang, H., and Wang, W. (2019). Electrospun gelatin nanofibers encapsulated with peppermint and chamomile essential oils as potential edible packaging. Journal of Agricultural and Food Chemistry, 67(8), 2227–2234.

Tiwari, P., Bharti, I., Bohidar, H. B., Quadir, S., Joshi, M. C., and Arfin, N. (2020). Complex coacervation and overcharging during interaction between hydrophobic zein and hydrophilic laponite in aqueous ethanol solution. ACS Omega, 5(51), 33064–33074.

Tortorella, S., Maturi, M., Buratti, V. V., Vozzolo, G., Locatelli, E., Sambri, L., and Franchini, M. C. (2021). Zein as a versatile biopolymer: Different shapes for different biomedical applications. RSC Advances, 11(62), 39004–39026.

Vigneshkumar, P. N., George, E., Joseph, J., John, F., and George, J. (2022). Liposomal Bionanomaterials for Nucleic Acid Delivery. In Fundamentals of Bionanomaterials (Barhoum, A., Jeevanandam, J., and Danquah M. K., Eds.), pp. 327–362. Amsterdam: Elsevier.

Wu, Y., Luo, Y., and Wang, Q. (2012). Antioxidant and antimicrobial properties of essential oils encapsulated in zein nanoparticles prepared by liquid–liquid dispersion method. LWT - Food Science and Technology. 48(2), 283–290.

Zhong, Q., and Jin, M. (2009). Zein nanoparticles produced by liquid–liquid dispersion. Food Hydrocolloids, 23(8), 2380–2387.

Zou, Y., Pan, R., Wan, Z., Guo, J., Wang, J., and Yang, X. (2017). Gel-like emulsions prepared with zein nanoparticles produced through phase separation from acetic acid solutions. International Journal of Food Science & Technology, 52(12), 2670–2676.