Roller compaction in pharmaceutical manufacturing: Comprehensive insights into processes, equipment, and formulation development
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Abstract
Roller compaction is a crucial operation in pharmaceutical manufacturing, offering a versatile approach to granulation and powder processing. This review provides a comprehensive overview of roller compaction in pharmaceutical production, including its principles, advantages, disadvantages, and recent trends. In addition, it explores formulation development for roller compaction, emphasizing critical quality attributes, suitable excipients, and the influence of material properties. Ultimately, this review is intended to serve as a valuable resource for pharmaceutical researchers, process engineers, and industry professionals aiming to enhance their understanding of roller compaction and its pivotal role in modern pharmaceutical manufacturing.
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