Chemical Constituents and Antimicrobial Activity of Essential Oil and Extracts of Heartwood of Aquilaria crassna Obtained from Water Distillation and Supercritical Fluid Carbon Dioxide Extraction
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Abstract
Agarwood (Aquilaria crassna) is a high value economic plant.Agarwood oil is widely used among variouscountries as perfumes and ingredient inmedical recipes. In this study, the extraction of driedAgarwood powderbywater distillation (WD), supercritical fluid carbon dioxide extraction (SFE) and SFEwith ethanol as cosolvent(SFE+co) gave 0.2%oil, 0.06%and 0.014%extracts, respectively. The types of chemical constituents of oil andextracts from these 3 extraction methods were quite similar. The major chemical constituents ofWD oil, SFEand SFE+co extracts were g-selinene (13.66%), selina-4,11-dien-14-al (14.25%) and selina-4,11-dien-14-al(13.39%), respectively. The WD oil, SFE and SFE+co extracts had antimicrobial activities against S. auruesand C. albicans, but were not sensitive to E. coli at maximum concentration of the study, 2mg/mL.
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