Green Pharmaceutical Chemistry for the Sustainability
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Keywords:
green environmentally friendly pharmaceutical chemistry sustainability
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Abstract
As a result of current environmental crises, the awareness and cooperation from all sectors are neededto help prevent and solve the problems. In pharmaceutical chemistry discipline, attempts have been madeto use the processes with the least adverse impacts on the environment. In this article, an overview of the“6-R” approach applicable to the development of greener methodologies for drug synthesis and analysisis presented and the paradigms of works are illustrated. It is also anticipated that the article will create theenvironmental conscience and promote the social responsibility for the development and use of eco-friendlierprocesses, leading to the sustainability.
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How to Cite
Rojanarata, T. (2013). Green Pharmaceutical Chemistry for the Sustainability. Science, Engineering and Health Studies, 6(1), 7–13. https://doi.org/10.14456/sustj.2012.1
Section
Invited Article
References
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Rojanarata, T., Isarangkul, D., Wiyakrutta, S., Meevootisom, V., and Woodley J. M. (2004). Controlled-release biocatalysis for the synthesis of D-phenylglycine. Biocatalysis and Biotransformation, 22(3): 195-201.
Rojanarata, T., Opanasopit, P., Ngawhirunpat, T., Saehuan, C., Wiyakrutta, S., and Meevootisom, V. (2010). A simple, sensitive and green bienzymatic UV-spectrophotometric assay of amoxicillin formulations. Enzyme and Microbial Technology, 46: 292–296.
Rojanarata, T., Sumran, K., Nateetaweewat, P., Winotapun, W., Sukpisit, S., Opanasopit, P., and Ngawhirunpat, T. (2011a). Microscale hemistry-based design of eco-friendly, reagent-saving and efficient pharmaceutical analysis: a miniaturized Volhard’s titration for the assay of sodium chloride. Talanta, 85: 1324-1329.
Rojanarata, T., Waewsa-nga, K., Buacheen, P., Opanasopit, P., and Ngawhirunpat T. (2011b). Development of greener and safer assays for hydrochloride drugs: photometric microtitration of phenylpropanolamine hydrochloride and metformin hydrochloride. Advanced Materials Research, 361-363: 1892-1896.
Rojanarata, T. (2011). Eco-friendly, operator-safe and cost-effective RP-HPLC method for stability-indicating assay of prednisolone tablets using ethanol-water as mobile phase. International Journal of Pharmacy and Pharmaceutical Sciences. Accepted manuscript.
Rojanarata, T., Isarangkul, D., Wiyakrutta, S., Meevootisom, V., and Woodley J. M. (2004). Controlled-release biocatalysis for the synthesis of D-phenylglycine. Biocatalysis and Biotransformation, 22(3): 195-201.
Rojanarata, T., Opanasopit, P., Ngawhirunpat, T., Saehuan, C., Wiyakrutta, S., and Meevootisom, V. (2010). A simple, sensitive and green bienzymatic UV-spectrophotometric assay of amoxicillin formulations. Enzyme and Microbial Technology, 46: 292–296.
Rojanarata, T., Sumran, K., Nateetaweewat, P., Winotapun, W., Sukpisit, S., Opanasopit, P., and Ngawhirunpat, T. (2011a). Microscale hemistry-based design of eco-friendly, reagent-saving and efficient pharmaceutical analysis: a miniaturized Volhard’s titration for the assay of sodium chloride. Talanta, 85: 1324-1329.
Rojanarata, T., Waewsa-nga, K., Buacheen, P., Opanasopit, P., and Ngawhirunpat T. (2011b). Development of greener and safer assays for hydrochloride drugs: photometric microtitration of phenylpropanolamine hydrochloride and metformin hydrochloride. Advanced Materials Research, 361-363: 1892-1896.