Principles of Pharmacotherapy in Pediatric Patients: Fundamental Pharmacological and Pharmacokinetic Knowledge and its Applicability

Main Article Content

Prayuth Poowaruttanawiwit
Kwanchai Rattanamanee

Abstract

This review article offers a comprehensive overview of the fundamental principles underpinning the management of pharmacotherapy in pediatric patients. Recognizing the distinct pharmacological and pharmacokinetic attributes of children is imperative for the safe and efficacious administration of drugs. By exploring critical concepts encompassing drug absorption, distribution, metabolism, and excretion within pediatric populations, healthcare providers can inform decisions when prescribing medications for children across all the age groups. Additionally, the implementation of pharmacokinetic/pharmacodynamic (PK/PD) principles in clinical practice assumes paramount importance in tailoring drug regimens to suit individual pediatric patients, thereby optimizing therapeutic outcomes and mitigating the potential for adverse events. As the landscape of pediatric pharmacotherapy research continues to advance, it is essential for healthcare professionals to remain up to date with the latest developments to ensure the provision of optimal care for this vulnerable patient demographic.

Article Details

Section
Review Articles
Author Biographies

Prayuth Poowaruttanawiwit, Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok 65000, Thailand

Medical and Pharmacy Innovation Research and Development Unit, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok 65000, Thailand

Kwanchai Rattanamanee, Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok 65000, Thailand

Medical and Pharmacy Innovation Research and Development Unit, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok 65000, Thailand

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