Main Article Content
Adverse reactions of antiepileptic drugs were being monitored prospectively in 560 outpatients (52.9% male) suffering from convulsive disorders in two major Bangkok Metropolitan hospitals. The patients were interviewed by trained observers using an open-ended question and a check list of known adverse reactions at least twice after receiving the drugs. Patients' medical records were also reviewed. Six different anti-epileptic drugs were being prescribed in the descending order: phenobarbital (42.5%), phenytoin (38.8%), carbamazepine (8.6%), clonazepam (6.4%), primidone(3.0%), and sodium valproate (0.7%). Nineteen percents of the patients reported some adverse effects of which 25% were sedation. Other adverse reactions were also related to central nervous system e.g. dizziness drowsiness, headache. No serious adverse effects were noted.
Upon acceptance of an article, the Pharmacological and Therapeutic Society of Thailand will have exclusive right to publish and distribute the article in all forms and media and grant rights to others. Authors have rights to use and share their own published articles.