Antifungal Activity of Alpinia Galanga and Allium Ascalonicum Extracts

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Keywords:
Piper betle Dermatophytes Antifungal effect

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Arinee Chatchawanchonteera
Department of Pathobiology, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen 40002
Wittaya Suriyasathaporn
Department of Physiology, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen 40002
Nopamart Trakranrungsie
Department of Pharmacology & Toxicology, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen 40002

Abstract

The objective of this study was to evaluate the inhibitory effects of Alpinia galanga (Zingiberaceae) and Allium ascalonicum (Liliaceae) on filamentous fungi (M.canis, M.gypseum and T.mentagophyte) and an opportunistic yeast (Candida albicans), using a broth dilution technique. The table showed the IC50±SEM and Emax±SEM of the plant extracts, compared to those of ketoconazole and griseofluvin. According to the IC50 values, the extract of A. galanga exhibited a more pronouncing effect against M. canis than other fungi, while the effect of A. ascalonicum on the tested microorganisms was not significantly different. Taken together with our previous study on the effect of Piper betle, it is concluded that both A. galanga and A. ascalonicum could serve as the alternatives for the antifungal recipes. However, possible side effects remain to be determined.

Article Details

Issue
Vol. 25 No. 1 (2003)
Section
2003 Annual Meeting Abstracts/Lectures

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