Biological Activities of Antidesma Thwaitesianum Muell
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Abstract
Antidesma thwaitesianum Muell is a member of Euphorbiaceae, some parts of it were
used to treatment several diseases worldwide but there is no scientific report. The objective of
this research is to test biological activity of all parts of this plant extract such as cytotoxic
activity against lung cancer cell by SRB assay, antioxidant activity by DPPH assay and
antimicrobial activity by disc diffusion method. The results found that the ethanolic extract
showed high antioxidant activity because they showed antioxidant activity more than BHT
(and wood exhibited the highest antioxidant activity. Antidesma thwaitesianum wood extract
also exhibited the highest cytotoxic against lung cancer cells. Its leaves extract showed the
highest antimicrobial against Staphyllococus aureus and Candida albican. In the conclusion,
wood of this plant appeared to be the best part used for cancer treatment because it showed
both antioxidant and cytotoxic activities and the leaves appeared to be the best part for
antimicrobial.
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