Drug-Induced Oesophageal Lesions

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Cha-onsin Sooksriwongse

Abstract

Drugs reported to cause oesophageal problems-i.e. ulceration, stricture or obstruction are reviewed. Medicines that remain in or adhere to the oesophageal wall will cause injuries. The incidence of retention of solid medications in the oesophagus is double in patients with oesophageal abnormality. The medicine should be taken with adequate amount of water, not in supine position or just before bedtime. This adverse effect can be reduced by both the development of safer dosage forms and providing the appropriate informations about drugs and their uses.

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