Reduction of Oximes
Keywords:
reduction, oximes, sodium borohydrideAbstract
The reduction of 8 oximes (6 ketoximes and 2 aldoximes) with sodium borohydride under acidic condition was studied. The reduction of certain oximes, particularly cyclohexanone oxime, gave corresponding N-monosubstituted hydroxylamines in comparable yield with the reduction with sodium cyanoborohydride under the same conditon. Aromatic ketoxime and aldoximes were poorly reduced and corresponding hydroxylamines were not obtained.
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online 2452-316X print 2468-1458/Copyright © 2022. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/),
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