Arachidonic Acid Conversion by Lipoxygenase in the Brown Alga, Laminaria angustata

Authors

  • Kangsadan Boonprab Department of Fishery Products Faculty of Fisheries, Kasetsart university, Bangkok 10900 Thailand.
  • Kenji Matsui Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University, Yamaguchi, 753-8515, Japan.
  • Yoshihiko Akakabe Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University, Yamaguchi, 753-8515, Japan.
  • Norishike Yotsukura Institute of Algological Research, Faculty of Science, Hokkaido University, Hokkaido, 051-0003, Japan.
  • Tadahiko Kajiwara Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University, Yamaguchi, 753-8515, Japan.

Keywords:

Brown algae, Laminaria angustata, Lipoxygenase, 11-Hydroperoxyeicosatetraenoic acid, 9-Hydroperoxyeicosatetraenoic acid, 8-Hydroperoxyeicosatetraenoic acid

Abstract

Arachidonic metabolism with the lipoxygenase to form its hydroperoxides (eicosanoids) has been commonly known in animal. Recently, we reported that eicosanoids, 12(S)- and 15(S)-hydroperoxyeicosatetraenoic acid were the intermediate product of major aldehyde flavor formation [3(Z)- and 2(E)- nonenal and n-hexanal] in an edible brown alga, Laminaria angustata via lipoxygenase (LOX) and hydroperoxide lyase pathway. Here another eicosanoides have been found after enzymatic formation and identified as 11-, 9-, 8- hydroperoxyeicosatetraenoic acid by HPLC and GC/GC-MS. They are believed to be the intermediate of physiological active compounds involving in chemical defense and sex pheromone. These represented the mechanism of positional selectivity of LOX in this marine alga.

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Published

2004-10-30

How to Cite

Kangsadan Boonprab, Kenji Matsui, Yoshihiko Akakabe, Norishike Yotsukura, and Tadahiko Kajiwara. 2004. “Arachidonic Acid Conversion by Lipoxygenase in the Brown Alga, Laminaria Angustata”. Agriculture and Natural Resources 38 (5). Bangkok, Thailand:72-77. https://li01.tci-thaijo.org/index.php/anres/article/view/243214.

Issue

Vol. 38 No. 5 (2004): September-October

Section

Research Article

License

online 2452-316X print 2468-1458/Copyright © 2022. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/),
production and hosting by Kasetsart University of Research and Development Institute on behalf of Kasetsart University.