Aerugine, an Antibiotic from Streptomyces fradiae Strain SU-1

Authors

  • Busaya Apichaisataienchote Department of Biotechnology, Silpakorn University, Nakhon Pathom 73000, Thailand.
  • Vichai Korpraditskul Department of Plant Pathology (Tropical Agriculture, International Program), Kasetsart University, Khampang Sean, Nakhon Pathom 73140, Thailand.
  • Serge Fotso Department of Organic and Biomolecular Chemistry, University of Goettingen, Tammanstrasse 2, D-37077 Goettingen, Germany.
  • Hartmut Laatsch Department of Organic and Biomolecular Chemistry, University of Goettingen, Tammanstrasse 2, D-37077 Goettingen, Germany.

Keywords:

aerugine, thiazoline, Streptomyces fradiae, Colletotrichum gloeosporioides, Phytophthora parasitica

Abstract

The antibiotic aerugine (4-hydroxymethyl-2-(2-hydroxyphenyl)-2-thiazoline) was isolated from the culture filtrate of Streptomyces fradiae strain SU-1 and purified by Sephadex LH-20 and silica gel column chromatography. The structure was determined by detailed interpretation of 1H, 13C NMR and
mass spectra. The minimum inhibitory concentrations (MIC) of aerugine were 12.5 μl/ml determined against both Colletotrichum gloeosporioides and Phytophthora parasitica. It completely inhibited conidial germination of C. gloeosporioides and inhibited encysted zoospore germination of P. parasitica.

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Published

2006-04-30

How to Cite

Busaya Apichaisataienchote, Vichai Korpraditskul, Serge Fotso, and Hartmut Laatsch. 2006. “Aerugine, an Antibiotic from Streptomyces Fradiae Strain SU-1”. Agriculture and Natural Resources 40 (2). Bangkok, Thailand:335-40. https://li01.tci-thaijo.org/index.php/anres/article/view/243608.

Issue

Vol. 40 No. 2 (2006): March-April

Section

Research Article

License

online 2452-316X print 2468-1458/Copyright © 2022. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/),
production and hosting by Kasetsart University of Research and Development Institute on behalf of Kasetsart University.