Genetic variation in KRTAP11.1 gene of Suri alpaca (Vicugna pacos) from Puno, Peru

Authors

  • Roberto Gallegos Veterinary Medicine School, Universidad Nacional del Altiplano, Puno, Peru
  • Jorge Rodriguez Molecular Biotechnology Unit, Universidad Peruana Cayetano Heredia, Lima, Peru
  • Ivan Quiñones Veterinary Medicine School, Universidad Nacional del Altiplano, Puno, Peru
  • Irene Delgado-de-la-Flor Molecular Biotechnology Unit, Universidad Peruana Cayetano Heredia, Lima, Peru
  • Teodosio Huanca Illpa Experimental Station, National Institute of Agrarian Innovation, Puno, Peru
  • Abigail de la Cruz Perez Veterinary Medicine School, Universidad Nacional del Altiplano, Puno, Peru
  • José R. Espinoza Molecular Biotechnology Unit, Universidad Peruana Cayetano Heredia, Lima, Peru

Keywords:

Alpaca, KAP11.1 gene, Keratin associated protein, Single nucleotide polymorphisms (SNPs), Suri

Abstract

The objective of this study was to identify genetic single nucleotide polymorphisms (SNPs) in the coding region of the KRTAP11.1 gene from the Suri alpaca population from Puno, Peru. Genomic DNA (n = 119) was used to amplify the 636 bp fragment of the coding region from the KRTAP11.1 gene. The polymerase chain reaction products of the KRTAP11.1 gene were sequenced by both strands and polymorphism type SNPs were identified. All SNPs (n = 3) were in Hardy-Weinberg equilibrium and had a high level of genotypic linkage disequilibrium with the presence of two haplotypes. All genetic polymorphisms generate non-synonymous amino acids changes: SNP 110 T>G (Ser>Ala), SNP 363 T>G (Phe>Cys) and SNP 375 A>C (Tyr>Ser). The results indicated the presence of moderate genetic diversity in the coding region of the KRTAP11.1 gene from the Suri alpaca population.

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Published

2019-02-28

How to Cite

Roberto Gallegos, Jorge Rodriguez, Ivan Quiñones, Irene Delgado-de-la-Flor, Teodosio Huanca, Abigail de la Cruz Perez, and José R. Espinoza. 2019. “Genetic Variation in KRTAP11.1 Gene of Suri Alpaca (Vicugna Pacos) from Puno, Peru”. Agriculture and Natural Resources 53 (1). Bangkok, Thailand:87-88. https://li01.tci-thaijo.org/index.php/anres/article/view/251662.

Issue

Vol. 53 No. 1 (2019): January-February

Section

Short Communication

License

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