Effect of green tea extract on blood glucose levels during Plasmodium berghei infection in mice

Authors

  • Ubonwan Jaihan Department of Clinical Chemistry, Faculty of Medical Technology, Western University, Kanchanaburi
  • Somdet Srichairatanakool Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai
  • Chairat Uthaipibull National Center for Genetic Engineering and Biotechnology (BIOTEC), National of Science and Technology Development Agency (NSTDA), Pathumthani
  • Voravuth Somsak Department of Clinical Chemistry, Faculty of Medical Technology, Western University, Kanchanaburi

DOI:

https://doi.org/10.14456/fabj.2014.10

Keywords:

blood glucose levels, green tea extract, Plasmodium berghei

Abstract

Hypoglycemia is recognized as a serious complication of malaria during Plasmodium infection in blood stage. Hence, this study was aimed to investigate the effect of green tea extract on blood glucose levels during Plasmodium berghei infection. Groups of naïve ICR mice were inoculated with 1x106 parasitized erythrocytes of P. berghei ANKA. Green tea extract (3,000 mg/kg) was given orally twice a day for 6 consecutive days, and blood glucose levels were subsequently measured. The results showed that levels of blood glucose were decreased significantly during malaria infection on day 6. Interestingly, blood glucose was maintained into normal levels in green tea extract treated PbANKA infected mice. It can be concluded that green tea extract was exerted glucose homeostasis during malaria infection.

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How to Cite

Jaihan, Ubonwan, Somdet Srichairatanakool, Chairat Uthaipibull, and Voravuth Somsak. 2017. “Effect of Green Tea Extract on Blood Glucose Levels During Plasmodium Berghei Infection in Mice”. Food and Applied Bioscience Journal 2 (2):126-34. https://doi.org/10.14456/fabj.2014.10.

Issue

Vol. 2 No. 2 (2014): May - August

Section

Food Processing and Engineering