Development of Skincare Emulsion Products from Curcuma longa L. and Terminalia bellirica (Gaertn.) Roxb. Extracts
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Abstract
The objectives of this research were to determine antioxidant activity of extracts of Curcuma longa L. and Terminalia bellirica (Gaertn.) Roxb., to examine curcuminoids complex content in the extracts of C. longa L. and to develop skincare emulsion products containing both extracts. The antioxidant activity of aqueous, 95% ethanol and acetonitrile extracts of C. longa L. and T. bellirica (Gaertn.) Roxb. was determined by using ABTS+ and DPPH methods. By using ABTS+ method, acetonitrile extract of C. longa L. and 95% ethanol extract of T. bellirica (Gaertn.) Roxb. exhibited the highest antioxidant properties with the IC50 of 0.269±0.018 and 0.104±0.004 mg/mL, respectively. By using DPPH method, acetonitrile extract of C. longa L. and aqueous extract of T. bellirica (Gaertn.) Roxb. exhibited the highest antioxidant properties with the IC50 of 1.951±0.013 and 0.337±0.0194 mg/mL, respectively. The study by high performance liquid chromatography revealed that the amounts of curcuminoids complex in aqueous, 95% ethanol and acetonitrile extracts of C. longa L. were 0.073±0.004, 305.60±0.05 and 330.60±0.45 mg/mL, respectively. The acetonitrile extract of C. longa L. and 95% ethanol extract of T. bellirica (Gaertn.) Roxb. were used to develop skincare emulsion products containing different type and amount of gelling agent. The most suitable formula with good emulsion characteristics and pH 6 contained 2% of Carbopol 940 as a gelling agent. This formula might be appropriate for usage as a skincare emulsion product for consumers who prefer using skincare products from natural extracts.
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บทความที่ได้รับการตีพิมพ์เป็นลิขสิทธิ์ของ วารสารวิทยาศาสตร์และเทคโนโลยี มหาวิทยาลัยอุบลราชธานี
ข้อความที่ปรากฏในบทความแต่ละเรื่องในวารสารวิชาการเล่มนี้เป็นความคิดเห็นส่วนตัวของผู้เขียนแต่ละท่านไม่เกี่ยวข้องกับมหาวิทยาลัยอุบลราชธานี และคณาจารย์ท่านอื่นๆในมหาวิทยาลัยฯ แต่อย่างใด ความรับผิดชอบองค์ประกอบทั้งหมดของบทความแต่ละเรื่องเป็นของผู้เขียนแต่ละท่าน หากมีความผิดพลาดใดๆ ผู้เขียนแต่ละท่านจะรับผิดชอบบทความของตนเองแต่ผู้เดียว
References
Cikrikci, S., Mozioglu, E. and Yilmaz, H. 2008. Biological activity of curcuminoids isolated from Curcuma longa. Records of Natural Products. 2(1): 19.
Labban, L. 2014. Medicinal and pharmacological properties of Turmeric (Curcuma longa): A review. International Journal of Pharmaceutical and Biomedical Sciences. 5(1): 17-23.
Kole, P.L. and et al. 2005. Cosmetic potential of herbal extracts. Chemical and Pharmaceutical Bulletin. 61(4): 419-425.
Goenka, S., Johnson, F. and Simon, S.R. 2021. Novel chemically modified curcumin (CMC) derivatives inhibit tyrosinase activity and melanin synthesis in B16f10 mouse melanoma cells. Biomolecules. 11(5): 674.
Balaji, S. and Chempakam, B. 2010. Toxicity prediction of compounds from turmeric (Curcuma longa L). Food and Chemical Toxicology. 48(10): 2951-2959.
Kaewtong, A. 2018. Effects of Triphala herbal formula in obesity stage 1 subjects at Maharaj Nakhon Si Thammarat Hospital. Maharaj Nakhon Si Thammarat Medical Journal. 2(1): 19-30. (in Thai)
Prathumtet, J. and et al. 2021. Comparison of antioxidant and anti-acne causing bacteria (P. acnes) activities of methanolic extracts from Triphala herbals. Journal of Traditional Thai Medical Research. 7(1): 2-14. (in Thai)
Braga, M.E. and et al. 2003. Comparison of yield, composition, and antioxidant activity of turmeric (Curcuma longa L.) extracts obtained using various techniques. Journal of Agricultural and Food Chemistry. 51(22): 6604-6611.
Net-anong, S. and et al. 2015. Free radical scavenging activity and total phenolic content of different times for extraction triphala powder and its stability study. Thammasat Medical Journal. 15(3): 472-479. (in Thai)
Sriset, Y., Chatuphonprasert, W. and Jarukamjorn, K. 2021. Bergenin attenuates sodium selenite-induced hepatotoxicity via improvement of hepatic oxidant-antioxidant balance in HepG2 cells and ICR mice. Journal of Biologically Active Products from Nature. 11(2): 97-115.
Chairgulprasert, V. and Kongsuwankeeree, K. 2017. Preliminary phytochemical screening and antioxidant activity of robusta coffee blossom. Science & Technology Asia. 22(1): 1-8.
Hazra, B. and et al. 2010. Comparative study of the antioxidant and reactive oxygen species scavenging properties in the extracts of the fruits of Terminalia chebula, Terminalia belerica and Emblica officinalis. BMC Complementary and Alternative Medicine. 10: 20.
Neves, M.I.L. and et al. 2020. Biorefinery of turmeric (Curcuma longa L.) using non-thermal and clean emerging technologies: An update on the curcumin recovery step. RSC Advances. 10(1): 112-121.
Kang, W.S. and et al. 1998. Antioxidative property of turmeric (Curcumae rhizoma) ethanol extract. Korean Journal of Food Science and Technology. 30(2): 266-271.
Khacharat, L. and et.al. 2015. Potentiality of endophytic fungi isolated from Thai medicinal plants in Piperaceae Family to control fungi causing postharvest decay of fruit. In: Proceedings of the 53rd Kasetsart University Annual Conference, 3-6 February 2015. Bangkok, Thailand. (in Thai)
Duanyai, S. and et al. 2021. Antioxidant activities, total phenolic and total flavonoid contents of Trisamor Trisutthakula and Tripholsamutthan. Journal of Traditional Thai Medical Research. 7(2): 93-104. (in Thai)
Nahak, G. and Sahu, R.K. 2011. Evaluation of antioxidant activity in ethanolic extracts of five curcuma species. International Research Journal of Pharmacy. 2(12): 243-248.
Amorati, R. and Valgimigli, L. 2018. Methods to measure the antioxidant activity of phytochemicals and plant extracts. Journal of Agricultural and Food Chemistry. 66: 3324-3329.
Badoni, H. and et al. 2016. Phytochemical analyses and evaluation of antioxidant, antibacterial and toxic properties of Emblica officinalis and Terminalia bellirica fruit extracts. Asian Journal of Pharmaceutical and Clinical Research. 9(6): 96-102.
Jaengklang, C. and et al. 2022. Study on total phenolic content, total flavonoid content and free radical scavenging activity in herbal extract. Journal of Traditional Thai Medical Research. 8(1): 93-106. (in Thai).
Thongchai, W. and et al. 2011. Analysis of curcuminoids in raw materials and cosmetic products from Curcuma spp. Life Sciences and Environment Journal. 12(2): 32-49. (in Thai)
Rachmawati, H., Budiputra, D.K. and Mauludin, R. 2015. Curcumin nanoemulsion for transdermal application: Formulation and evaluation. Drug Development and Industrial Pharmacy. 41(4): 560-566.
