Total Phenolic Content, Total Flavonoid Content and Anti-Streptococcus mutants Activity of Chan Tung Ha Extracts
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Abstract
Chan Tung Ha is a Thai herbal medicinal recipe for fever relief, treatment of mouth ulcer, and maintenance of liver, lung, and heart. It consists of 5 types of heartwoods including Tarenna hoaensis Pit., Dracaena loureiroi Gagnep., Santalum album., Myristica fragrans Houtt. and Mansonia gagei. At present, there are very few reports on Chan Tung Ha’s inhibitory activity against Streptococcus mutans, a bacterial pathogen causing oral diseases and dental caries. This research aimed to determine total phenolic content and total flavonoid content and to examine anti-Streptococcus mutans of ethanol extract of Chan Tung Ha and ethanol extracts of individual herbal ingredients of Chan Tung Ha. The results revealed that the Dracaena loureiroi Gagnep. extract had the highest total phenolic content of 93.06 ± 6.67 mg gallic acid equivalent/g of dry extract while the Tarenna hoaensis Pit. extract had the highest total flavonoid content of 83.00 ± 9.84 mg quercetin equivalent/g of dry extract. Furthermore, it was also found that the extracts of Dracaena loureiroi Gagnep., Santalum album. and Tarenna hoaensis Pit. exhibited the highest anti-S. mutans activity with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of 15.62 ± 0.00 and 31.25 ± 0.00 mg/mL, respectively. Therefore, Chan Tung Ha recipe and its individual herbal ingredients have the potential to be further developed for use in treating oral diseases caused by S. mutans infection.
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บทความที่ได้รับการตีพิมพ์เป็นลิขสิทธิ์ของ วารสารวิทยาศาสตร์และเทคโนโลยี มหาวิทยาลัยอุบลราชธานี
ข้อความที่ปรากฏในบทความแต่ละเรื่องในวารสารวิชาการเล่มนี้เป็นความคิดเห็นส่วนตัวของผู้เขียนแต่ละท่านไม่เกี่ยวข้องกับมหาวิทยาลัยอุบลราชธานี และคณาจารย์ท่านอื่นๆในมหาวิทยาลัยฯ แต่อย่างใด ความรับผิดชอบองค์ประกอบทั้งหมดของบทความแต่ละเรื่องเป็นของผู้เขียนแต่ละท่าน หากมีความผิดพลาดใดๆ ผู้เขียนแต่ละท่านจะรับผิดชอบบทความของตนเองแต่ผู้เดียว
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