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The purposes of this research were to develop teaching and learning skills in transcultural nursing using e-learning for Cambodian nursing students based on an 80/80 criteria, study the need and readiness for e-learning before and after teaching and learning and study Cambodian nursing students’ satisfaction with teaching and learning. In academic year 2018, 17 Cambodian nursing students from the University of Puthisastra, Cambodia, registered in the transcultural nursing program for the Bachelor of Health Sciences, Nursing Bridging program at Saint Louis Collaege, Thailand. The tools used for the research included learning needs and readiness assessment form, a knowledge assessment form, and a satisfaction assessment form on teaching and learning using e-learning. The results revealed that the subjects’ achievements from learning in transcultural nursing using e-learning during their learning and post-learning periods, based on 80/80 criteria, were better. The average scores of readiness and need for teaching and learning using e-learning in the post-test were significantly greater than the pre-test. The subjects’ satisfaction from teaching and learning in transcultural nursing using e-learning was at a good level. The findings indicated that interesting and suitable teaching and learning encouraged learners to pay attention to learning, leading to further study and research apart from lessons, and trying to solve problems and obstacles so that learning continues. As a result, students will have fun, feel happy, and understand their lessons more completely. Therefore, teaching and learning using e-learning is a learning style that may suit learners in the modern age, whereby development must be focused on further enhancement.
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