Antioxidation and anti-melanogenesis of three colored flowers of Dendrobium hybrids

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Published: Oct 31, 2022
DOI: https://doi.org/10.14456/sehs.2022.22
Keywords:
Dendrobium orchid extracting condition antioxidant tyrosinase inhibition activity anti-melanogenesis activity

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Kalyanee Jirasripongpun
Department of Biotechnology, Faculty of Engineering and Industrial Technology, Silpakorn University, Nakhon Pathom, Thailand. Corresponding author's e-mail: jirasripongpun_k@su.ac.th
Nuananong Jirakanjanakit
Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand
Sunita Pola
Department of Biotechnology, Faculty of Engineering and Industrial Technology, Silpakorn University, Nakhon Pathom, Thailand
Kullanart Obsuwan
Department of Biology, Faculty of Science, Silpakorn University, Nakhon Pathom, Thailand

Abstract

Dendrobium is one of the major tropical orchid cut flowers for trading. The unqualified materials could possibly be used as sources of cosmetic ingredients. In this study, flowers of the Dendrobium hybrids, namely D. Sonia ‘Jo Daeng’ (purple), D. Khoa Sanan (white) and D. Black Pearl (purple black), were ethanolic extracted and determined for anti-melanogenesis activity. The optimum extracting condition based on antioxidant capacity using DPPH assay was sonicated, following with 100 rpm shaking at 50ºC for 6 h. While D. Black Pearl extract exhibited the highest total phenolic and flavonoid contents, D. Sonia ‘Jo Daeng revealed the strongest DPPH scavenging activity. D. Khao Sanan extract had the highest metal chelating activity and anti-mushroom tyrosinase activity. All the extracts showed no cytotoxicity at the highest tested concentration (400 µg/mL). It was observed that D. Khao Sanan treated cells contained the lowest cellular melanin content. This implied that the metal chelating activity of the extracts exhibited some relationship to tyrosinase inhibition activity, which could be a useful screening assay for anti-melanogenesis agents. With relative effectiveness in melanogenesis inhibition to kojic acid, D. Khao Sanan orchid may be an applicable source of natural agent for skin lightening in cosmetic products.

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How to Cite
Jirasripongpun, K. ., Jirakanjanakit, N., Pola, S., & Obsuwan, K. (2022). Antioxidation and anti-melanogenesis of three colored flowers of Dendrobium hybrids. Science, Engineering and Health Studies, 16, 22030006. https://doi.org/10.14456/sehs.2022.22
Issue
Volume 16, 2022
Section
Biological sciences
Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Author Biography

Nuananong Jirakanjanakit, Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand

 

 

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