Antioxidation and anti-melanogenesis of three colored flowers of Dendrobium hybrids

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Published: Oct 31, 2022
DOI: https://doi.org/10.14456/sehs.2022.22
Keywords:
Dendrobium orchid extracting condition antioxidant tyrosinase inhibition activity anti-melanogenesis activity

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Kalyanee Jirasripongpun
Department of Biotechnology, Faculty of Engineering and Industrial Technology, Silpakorn University, Nakhon Pathom, Thailand. Corresponding author's e-mail: [email protected]
Nuananong Jirakanjanakit
Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand
Sunita Pola
Department of Biotechnology, Faculty of Engineering and Industrial Technology, Silpakorn University, Nakhon Pathom, Thailand
Kullanart Obsuwan
Department of Biology, Faculty of Science, Silpakorn University, Nakhon Pathom, Thailand

Abstract

Dendrobium is one of the major tropical orchid cut flowers for trading. The unqualified materials could possibly be used as sources of cosmetic ingredients. In this study, flowers of the Dendrobium hybrids, namely D. Sonia ‘Jo Daeng’ (purple), D. Khoa Sanan (white) and D. Black Pearl (purple black), were ethanolic extracted and determined for anti-melanogenesis activity. The optimum extracting condition based on antioxidant capacity using DPPH assay was sonicated, following with 100 rpm shaking at 50ºC for 6 h. While D. Black Pearl extract exhibited the highest total phenolic and flavonoid contents, D. Sonia ‘Jo Daeng revealed the strongest DPPH scavenging activity. D. Khao Sanan extract had the highest metal chelating activity and anti-mushroom tyrosinase activity. All the extracts showed no cytotoxicity at the highest tested concentration (400 µg/mL). It was observed that D. Khao Sanan treated cells contained the lowest cellular melanin content. This implied that the metal chelating activity of the extracts exhibited some relationship to tyrosinase inhibition activity, which could be a useful screening assay for anti-melanogenesis agents. With relative effectiveness in melanogenesis inhibition to kojic acid, D. Khao Sanan orchid may be an applicable source of natural agent for skin lightening in cosmetic products.

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How to Cite
Jirasripongpun, K. ., Jirakanjanakit, N., Pola, S., & Obsuwan, K. (2022). Antioxidation and anti-melanogenesis of three colored flowers of Dendrobium hybrids. Science, Engineering and Health Studies, 16, 22030006. https://doi.org/10.14456/sehs.2022.22
Issue
Volume 16, 2022
Section
Biological sciences
Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Author Biography

Nuananong Jirakanjanakit, Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand

 

 

References

Athipornchai, A., and Jullapo, N. (2018). Tyrosinase inhibitory and antioxidant activities of orchid (Dendrobium spp.). South African Journal of Botany, 119, 188-192.

Cabanes, J., Chazarra, S., and Garcia-Carmona, F. (1994). Kojic acid, a cosmetic skin whitening agent, is a slow-binding inhibitor of catecholase activity of tyrosinase. Journal of Pharmacy and Pharmacology, 46(12), 982-985.

Cakova, V., Bonte, F., and Lobstein, A. (2017). Dendrobium: Sources of active ingredients to treat age-related pathologies. Aging and Disease, 8(6), 827-849.

Chan, C. F., Wu, C. T., Huang, W. Y., Lin, W. S., Wu, H. W., Huang, T. K., Chang, M. Y., and Lin, Y. S. (2018). Antioxidation and melanogenesis inhibition of various Dendrobium tosaense extracts. Molecules, 23(7), 1810.

Chen, M. J., Hung, C. C., Chen, Y. R., Lai, S. T., and Chan, C. F. (2016). Novel synthetic kojic acid-methimazole derivatives inhibit mushroom tyrosinase and melanogenesis. Journal of Bioscience and Bioengineering, 122(6), 666-672.

Dinis, T. C. P., Madeira, V. M. C., and Almeida, L. M. (1994). Action of phenolic derivatives (acetaminophen, salicylate, and 5-aminosalicylate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers. Archives of Biochemistry and Biophysics, 315(1), 161-169.

Kanlayavattanakul, M., and Lourith, N. (2020). Orchid extracts and cosmetic benefits. In Orchids Phytochemistry, Biology and Horticulture (Mérillon, J. M., and Kodja, H., eds.), pp. 609-626. Cham: Springer.

Kubo, I., Kinst-Hori, I., Chaudhri, S. K., Kubo, Y., Sánchez, Y., and Ogura, T. (2000). Flavonols from heterotheca inuloides: tyrosinase inhibitory activity and structural criteria. Bioorganic & Medicinal Chemistry, 8(7), 1749-1755.

Lam, Y., Ng, T. B., Yao, R. M., Shi, J., Xu, K., Sze, S. C. W., and Zhang, K. Y. (2015). Evaluation of chemical constituents and important mechanism of pharmacological biology in Dendrobium plants. Evidence-based Complement and Alternative Medicine, 841752.

Liu, M., Li, X. Q., Weber, C., Lee, C. Y., Brown, J., and Liu, R. H. (2002). Antioxidant and antiproliferative activities of raspberries. Journal of Agricultural and Food Chemistry, 50(10), 2926-2930.

Lu, H., Yang, K., Zhan, L., Lu, T., Chen, X., Cai, X., Zhou, C., Li, H., Qian, L., Lv, G., and Chen, S. (2019). Optimization of flavonoid extraction in Dendrobium officinale leaves and their inhibitory effects on tyrosinase activity. International Journal of Analytical Chemistry, 7849198.

Maisuthisakul, P., Suttajit, M., and Pongsawatmanit, R. (2005). Assessment of phenolic content and free radical scavenging capacity of some Thai indigenous plants. Food Chemistry, 100(4), 1409-1418.

Masuda, T., Yamashita, D., Takeda, Y., and Yonemori, S. (2005). Screening for tyrosinase inhibitor among extract of seashore plant and identification of potent inhibitors from Garcinia subelliptica. Bioscience, Biotechnology, and Biochemistry, 69(1), 197-201.

Nakagawa, M., Kawai, K., and Kawai, K. (1995). Contact allergy to kojic acid in skin care products. Contact Dermatitis, 32(1), 9-13.

Nguyen, H. C., Lin, K. H., Huang, M. Y., Yang, C. M., Shih, T. H., Hsiung, T. C., Lin, Y. C., and Tsao, F. C. (2018). Antioxidant activities of the methanol extracts of various parts of phalaenopsis orchids with white, yellow, and purple flowers. Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 46(2), 457-465.

Obsuwan, K., Jeong, B. R., and Maksup, S. (2019). Analysis of bioactive compounds, polysaccharides and antioxidant activity in different parts of Dendrobium 'Sonia Jo Daeng'. Science, Engineering and Health Studies, 13(2), 73-82.

Paudel, M. R., Chand, M. B., Karki, N., and Pant, B. (2015). Antioxidant activity and total phenolic and flavonoid contents of Dendrobium amoenum Wall. ex Lindl. Botanica Orientalis Journal of Plant Science, 9, 20-26.

Rattanachitthawat, S., Suwannalert, P., Riengrojpitak, S., Chaiyasut, C., and Pantuwatana, S. (2010). Phenolic content and antioxidant activities in red unpolished Thai rice prevents oxidative stress in rats. Journal of Medicinal Plants Research, 4(9), 796-801.

Sompong, R., Siebenhandl-Ehn, S., Linsberger-Martin, G., and Berghofer, E. (2011). Physicochemical and antioxidative properties of red and black rice varieties from Thailand, China and Sri Lanka. Food Chemistry, 124(1), 132-140.

Wang, D., Fan, B., Wang, Y., Zhang, L., and Wang, F. (2018). Optimum extraction characterization and antioxidant activities of polysaccharides from flower of the Dendrobium devonianum. International Journal of Analytical Chemistry, 3013497.

Wei, C. I., Huang, T. S., Fernando, S. Y., and Chung, K. T. (1991). Mutagenicity studied of kojic acid. Toxicology Letters, 59(1-3), 213-220.

Xu, J., Han, Q. B., Li, S. L., Chen, X. J., Wang, X. N., Zhao, Z. Z., and Chen, H. (2013). Chemistry, bioactivity and quality control of Dendrobium, a commonly used tonic herb in traditional Chinese medicine. Phytochemical Review, 12(2), 341-367.