Evaluation of the Biological Activities of Sung Yod Germinated Brown Rice Extract Soaking in Pandanus Leaf Extract

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ชุติมา แก้วพิบูลย์
ณวงศ์ บุนนาค

Abstract

Nowadays, the consumption of germinated brown rice is becoming a popular health food because of their high nutritional value. Therefore, the aim of this research was to study antioxidant and biological activities of the Sung Yod germinated brown rice (SGBr) extract which was soaked in Pandanus leaf extract (PE), i.e. the antioxidant activities assay by DPPH and ABTS methods, inhibitory activity of tyrosinase, and cytotoxicity assay against HaCaT cell lines with MTT method. From the results, SGBr extract showed total phenolic content of 134.52 mg GAE/g extract. The antioxidant activity assays by DPPH and ABTS method showed EC50 values of 53.42 and 9.92 µg/mL, respectively, which were more effective than control significantly at the confidence level of 95 %. In addition, the SGBr extract showed the inhibitory activity of tyrosinase with IC50 value of 3.14 µg/mL. Moreover, cytotoxicity assay against HaCaT cell lines showed IC50 values of more than 400 µg/mL. It is very interesting for the development of the SGBr extract as a cosmetic product.


 

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Section
วิทยาศาสตร์ชีวภาพ
Author Biographies

ชุติมา แก้วพิบูลย์

สาขาวิชาชีววิทยา คณะวิทยาศาสตร์ มหาวิทยาลัยทักษิณ วิทยาเขตพัทลุง ตำบลบ้านพร้าว อำเภอป่าพะยอม จังหวัดพัทลุง 93210

ณวงศ์ บุนนาค

สาขาวิชาวิทยาศาสตร์และคณิตศาสตร์พื้นฐาน คณะวิทยาศาสตร์ มหาวิทยาลัยทักษิณ วิทยาเขตสงขลา ตำบลเขารูปช้าง อำเภอเมือง จังหวัดสงขลา 90000

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