Dosimetric Comparison of Esophageal Cancer Treatment Planning for VMAT technique Using 6 and 10 MV Photon Beams
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Abstract
Volumetric Modulated Arc Therapy (VMAT) is one of the most common treatment techniques for esophageal cancer, which can give the radiation dose to conform to the tumor shape. However, the tumor dose and normal tissue dose depend on the photon energy. The purpose of the study is to compare the dosimetric data of PTV and OARs using 6 MV and 10 MV photon beams for VMAT plans for esophagus cancer. A retrospective data from the VMAT treatment plan of 17 esophageal cancer cases was replanned using 6 and 10 MV photon beams. The dosimetric parameter of PTV and OARs, skin dose, and monitor units were collected. The data was analyzed by using Wilcoxon rank sums test. The p-value <0.05, the difference was considered statistically significant. The result showed that the mean values of dosimetric data in PTV, OAR, Skin dose, and MU parameters were not significantly different. The percentage difference varied between 0.02-6.41. However, skin doses and MUs of 10 MV VMAT plans were less than 6 MV VMAT plans. In conclusion the tumor dose and normal tissue dose between using 6 MV and 10 MV photon beams were not different. Furthermore, skin doses and treatment time of 10 MV VMAT plans were reduced. Finally, the VMAT plan with a 10 MV photon beam can be selected to use for esophagus cancer.
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National Cancer Institute, Cancer Registry 2021, Avalable Source: https://www.nci.go.th/e_book/hosbased_2564/index.html, November 8, 2022. (in Thai)
World Cancer Research Fund, Worldwide cancer data, Avalable Source: https://www.wcrf.org/cancer-trends/worldwide-cancer-data/, November 8, 2022.
National Cancer Institute, Esophageal cancer, Avalable Source: https://www.nci.go.th/th/Knowledge/downloads/0020.pdf?fbclid=Iw%20AR2xq35mdHbkAeMtU8SXFmbHv3pXoQ18Ys-T0hL-HO50syvALDXbPqsKGgg, November 8, 2022. (in Thai)
Chulacancer, King Chulalongkorn Memorial Hospital, Volumetric Modulated Arc Therapy, Avalable Source: https://www.chulacancer.net/services-list-page.php?id=441, November 8, 2022. (in Thai)
Radiosurgery center, Faculty of Medicine Ramathibodi Hospital, What is Radiotherapy, Avalable Source: https://www.rama.mahidol.ac.th/radiosurgery_center/th/km/15sep2021-1059, September 23, 2022. (in Thai)
Bumrungrad Hospital, Volumetric Modulated Arc Therapy, Avalable Source: https://www.bumrungrad.com/th/treatments/vmat-radiotherapy, November 8, 2022. (in Thai)
Yadav G., Bhushan M., Dewan A., Saxena U., Kumar L., Chauhan D., 2017, Dosimetric influence of photon beam energy and number of arcs on volumetric modulated arc therapy in carcinoma cervix: A planning study. Rep. Pract. Oncol. Radiother. 22: 1–9.
Pasler M., Georg D., Wirtz H., Lutterbach J., 2011, Effect of photon-beam energy on VMAT and IMRT treatment plan quality and dosimetric accuracy for advanced prostate cancer. Strahlenther. Onkol. Organ Dtsch Rontgengesellschaft Al. 187: 792–798.
Kleiner H., Podgorsak M.B., 2016, The dosimetric significance of using 10 MV photons for volumetric modulated arc therapy for post-prostatectomy irradiation of the prostate bed. Radiol. Oncol. 50:232–237.
Stanley D.N., Popp T., Ha C.S., Swanson G.P., Eng T.Y., Papanikolaou N., 2015, Dosimetric effect of photon beam energy on volumetric modulated arc therapy treatment plan quality due to body habitus in advanced prostate cancer. Pract. Radiat. Oncol. 5: 625–633.
Mattes M.D., Tai C., Lee A., Ashamalla H., Ikoro N.C., 2014, The dosimetric effects of photon energy on the quality of prostate volumetric modulated arc therapy. Pract. Radiat. Oncol. 4: 39–44.
Worrapipat S., Damrongkijudom N., Tangboonduangjit P., Sanghangthum T., 2016, Comparative Dosimetric Analysis of Lung Cancer Treatment Planning for 3D-CRT Using 6 and 10 MV Photon Beams. Ramathibodi Med. J. 39: 100–109.
Atiq M., Atiq A., Iqbal K., Shamsi Q., Andleeb F., Buzdar S.A., 2017, Evaluation of dose conformity and coverage of target volume for intensity-modulated radiotherapy of pelvic cancer treatment. Indian J. Cancer. 54: 379–384.
Guo X.Q., Mao R.H., Liu B., Ge H., 2023, Study on esophageal cancer radiotherapy dosimetry and position verification for volumetric modulated arc therapy. Asian J. Surg. 46: 120–125.
Onal C., Arslan G., Parlak C., Sonmez S., 2014, Comparison of IMRT and VMAT plans with different energy levels using Monte-Carlo algorithm for prostate cancer. Jpn. J. Radiol. 32: 224–232.
Bisello S., Cilla S., Benini A., Cardano R., Nguyen N.P., Deodato F., 2022, Dose–Volume Constraints fOr oRganS At risk In Radiotherapy (CORSAIR): An “All-in-One” Multicenter–Multidisciplinary Practical Summary. Curr. Oncol. 29: 7021–7050.
Kry S.F., Smith S.A., Weathers R., Stovall M., 2012, Skin dose during radiotherapy: a summary and general estimation technique. J. Appl. Clin. Med. Phys. 13: 20–34.