Assay of Acetaminophen in Paracetamol Tablets by Differential Pulse Voltammetry

ผู้แต่ง

  • Duncan Thorburn Burns Department of Analytical Chemistry, The Queen’s University of Belfast BT9 5AG UK.
  • Nipon Tungkananuruk Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.
  • Sumaporn Kasemsumran Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.
  • Kanita Tungkananuruk Department of Chemistry, Faculty of Science, King Mongkut’s Institute of Technology, Lardkrabang, Bangkok 10520, Thailand.

คำสำคัญ:

acetaminophen, paracetamol, differential pulse voltammetry, glassy carbon electrode

บทคัดย่อ

A simple and precise procedure using differential pulse voltammetry was developed for the assay of acetaminophen in paracetamol tablets. The peak current from acetaminophen in 0.1 mol L-1 phosphate buffer pH 7.0 was measured using a glassy carbon electrode and a Ag/AgCl reference electrode. The optimum step potential and modulation amplitude were 0.0020 and 0.0500 V, respectively. The linear calibration range was 0-300 μg ml-1, the detection limit and recovery were 0.15 μg ml-1 and 99.4%, respectively. The results were compared with those obtained by the U.S.P XXII official method.

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เผยแพร่แล้ว

2004-08-30

How to Cite

Duncan Thorburn Burns, Nipon Tungkananuruk, Sumaporn Kasemsumran, และ Kanita Tungkananuruk. 2004. “Assay of Acetaminophen in Paracetamol Tablets by Differential Pulse Voltammetry”. Agriculture and Natural Resources 38 (4). Bangkok, Thailand:510-14. https://li01.tci-thaijo.org/index.php/anres/article/view/243200.

ฉบับ

ปีที่ 38 ฉบับที่ 4 (2004): July-August

บท

Research Article

License

online 2452-316X print 2468-1458/Copyright © 2022. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/),
production and hosting by Kasetsart University of Research and Development Institute on behalf of Kasetsart University.