Assay of Acetaminophen in Paracetamol Tablets by Differential Pulse Voltammetry

ผู้แต่ง

  • Duncan Thorburn Burns Department of Analytical Chemistry, The Queen’s University of Belfast BT9 5AG UK.
  • Nipon Tungkananuruk Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.
  • Sumaporn Kasemsumran Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.
  • Kanita Tungkananuruk Department of Chemistry, Faculty of Science, King Mongkut’s Institute of Technology, Lardkrabang, Bangkok 10520, Thailand.

คำสำคัญ:

acetaminophen, paracetamol, differential pulse voltammetry, glassy carbon electrode

บทคัดย่อ

A simple and precise procedure using differential pulse voltammetry was developed for the assay of acetaminophen in paracetamol tablets. The peak current from acetaminophen in 0.1 mol L-1 phosphate buffer pH 7.0 was measured using a glassy carbon electrode and a Ag/AgCl reference electrode. The optimum step potential and modulation amplitude were 0.0020 and 0.0500 V, respectively. The linear calibration range was 0-300 μg ml-1, the detection limit and recovery were 0.15 μg ml-1 and 99.4%, respectively. The results were compared with those obtained by the U.S.P XXII official method.

ดาวน์โหลด

เผยแพร่แล้ว

2004-08-30

รูปแบบการอ้างอิง

Duncan Thorburn Burns, Nipon Tungkananuruk, Sumaporn Kasemsumran, และ Kanita Tungkananuruk. 2004. “Assay of Acetaminophen in Paracetamol Tablets by Differential Pulse Voltammetry”. Agriculture and Natural Resources 38 (4). Bangkok, Thailand:510-14. https://li01.tci-thaijo.org/index.php/anres/article/view/243200.

ฉบับ

ประเภทบทความ

Research Article