Biological Activities of Curcuma zedoaria (Christm.) Roscoe

Abstract

Curcuma zedoaria is a medicinal plant belonging to the family of Zingiberaceae which contains active compounds as curcuminoids. Moreover, C. zedoaria shows a wide range of biological activities. Therefore, the aim of this research was to study biological activities of C. zedoaria extracted by ethanol. The results were shown that crude extract exhibited total phenolic compounds of 84.32.2.21 mg GAE/g extract. The antioxidant activities assay by DPPH and ABTS method showed EC₅₀ values of 150.00±10.00 and 110.00±5.21 µg/mL, respectively. In addition, the crude extract showed the inhibitory activity of tyrosinase with IC₅₀ values of 102.5±38.89 µg/mL. Furthermore, ethanol crude extract of C. zedoaria non-cytotoxicity against HaCaT cell lines showed IC₅₀ values more than 200 µg/mL. Therefore, it is very interesting for the development of the C. zedoaria extract as a diverse cosmeceutical, medicinal and food additives applications.