STUDY OF GEL FORMULATION FROM BARK OF TINOSPORA CRISPA EXTRACT WITH INFLAMMATORY ACNE
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Abstract
This research is a qualitative research. The purpose of this research was studied to compare maceration and soxhlet extraction methods with 95% ethanol from bark of Tinospora crispa and development of gel formulation form bark of T. crispa with inflammatory acne. Then, absorbance to measure at wavelength 292 and 319 nanometer by UV-VIS spectrophotometer. After that, the development to gel formulation with physical property, chemical property and stability tests by freeze thaw cycles. The results showed that the T. crispa extract with maceration method have %yield as 18.81 more than 7.76 to compare with soxhlet extraction as 11.05, respectively. The suitable concentration for the stability test of the extract in the formulation was 0.30 mg/mL and the formulation of 1.0% Carbopol® 940 with crude extract of T. crispa was the highest stability.
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