การเฝ้าระวังเชิงรุกของเชื้อ Cryptococcus neoformans ในสวนสัตว์นครราชสีมา ประเทศไทย

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สุดาลักษณ์ ธัญญาหาร
วิรงรอง ช่างเพชร
นิจธร สังข์ศิรินทร์
พลวรรต ทองสุข
ทัศนีย์ เสาวนะ
ปฏิวัติ ราษี
ประกายกานต์ กอผา
ธนิต บุญศิริ

บทคัดย่อ

Cryptococcus neoformans เป็นเชื้อราก่อโรค cryptococcosis ทั้งในคนและสัตว์ เชื้อชนิดนี้มักพบในมูลนก การติดเชื้อจากสัตว์สู่คนโดยการหายใจเอาเชื้อเข้าไปทำาให้เกิดปอดอักเสบ เชื้อสามารถแพร่กระจายไปที่ระบบประสาทส่วนกลางทำาให้เกิดโรคเยื่อหุ้มสมองอักเสบซึ่งอาจเป็นอันตรายถึงชีวิต เพื่อเป็นการเฝ้าระวังและป้องกันการแพร่กระจายของเชื้อชนิดนี้ในสวนสัตว์นครราชสีมา ประเทศไทย ทั้งจากนกสู่นกหรือนกสู่คน งานวิจัยนี้ได้สำารวจอุบัติการณ์ของเชื้อ C. neoformans ในมูลนกชนิดต่างๆ ของสวนสัตว์นครราชสีมาในช่วงเดือนเมษายน พ.ศ. 2564 โดยเก็บมูลนกสดในกรงเลี้ยงนก 29 ชนิด ของนกในกลุ่มต่างๆ ได้แก่ นกกระเรียน 5 ชนิด ไก่ฟ้า 8 ชนิด นกเงือก 4 ชนิด นกแก้ว 4 ชนิด นกกระสา 3 ชนิด นกกระทุง 1 ชนิด นกล่าเหยื่อ 1 ชนิด รวมทั้งนกบินไม่ได้ ได้แก่ นกอีมู นกคาสโซวารีและนกเพนกวิน อย่างละ 1 ชนิด ได้จำานวนมูลนก 67 ตัวอย่าง นำามาเพาะแยกเชื้อบนอาหารเลี้ยงเชื้อ Sabouraud dextrose agar (SDA) ที่เติมยาคลอแรมเฟนิคอลและสารสกัดจากเมล็ดทานตะวัน พบว่ามูลนกทั้งหมดตรวจไม่พบเชื้อ C. neoformans แต่อย่างไรก็ตาม การเฝ้าระวังเชื้อ C. neoformans ในสวนสัตว์ควรดำาเนินการศึกษาอย่างต่อเนื่อง

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References

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