ฤทธิ์ทางชีวภาพจากโปรตีนไหมเซริซินและการนำไปใช้ประโยชน์
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บทคัดย่อ
โปรตีนเซริซิน (Sericin protein) หรือโปรตีนกาวไหม (Silk glue protein) จัดเป็นพอลิเมอร์ทางชีวภาพชนิดหนึ่งที่ผลิตจากหนอนไหม มีฤทธิ์ทางชีวภาพที่เป็นประโยชน์หลากหลาย โดยในช่วงทศวรรษที่ผ่านมา กาวไหมได้รับความสนใจเป็นอย่างมากสำหรับนำไปประยุกต์ใช้ทางชีวการแพทย์ และเวชสำอางเนื่องจากคุณสมบัติทางชีวภาพที่เข้ากันได้กับร่างกายและสามารถย่อยสลายได้ตามธรรมชาติ รวมทั้งยังมีฤทธิ์ที่เป็นประโยชน์มากมายที่เกิดจากกรดแอมิโนที่เป็นองค์ประกอบในกาวไหมอีกด้วย บทความปริทัศน์นี้จะกล่าวถึงโครงสร้างและองค์ประกอบรวมถึงคุณสมบัติทางชีวภาพของกาวไหม วิธีต่างๆที่ใช้ในการลอกกาวไหมและการนำไปประยุกต์ใช้ในทางการแพทย์เช่นการรักษาโรคเฉพาะและการส่งเสริมการฟื้นฟูเนื้อเยื่อ รวมถึงฤทธิ์ในการต้านอนุมูลอิสระ ฤทธิ์ส่งเสริมการเจริญของเซลล์ และฤทธิ์ทางชีวภาพอื่นๆ บทความนี้ยังกล่าวการนำกาวไหมไปสร้างวัสดุชีวภาพและความก้าวหน้าในการนำไปใช้ในทางวิศวกรรมเนื้อเยื่อและการนำส่งยาและงานวิจัยที่จะช่วยเสริมศักยภาพของวัสดุชีวภาพจากกาวไหม
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