การประเมินศักยภาพของสารสกัดจากกากกาแฟเพื่อเป็นทางเลือกทดแทนยาปฏิชีวนะกระตุ้นการเจริญเติบโตในไก่เนื้อ
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สารสกัดจากกากกาแฟ (Spent coffee ground extracts; SCGE) อุดมไปด้วยกรดคลอโรจีนิก และเมลาโนดินเหมาะสำหรับเสริมในอาหารสัตว์เพื่อปรับปรุงประสิทธิภาพการผลิต การศึกษาครั้งนี้มีวัตถุประสงค์เพื่อศึกษาผลของการเสริม SCGE ในอาหารต่อประสิทธิภาพการเจริญเติบโต ค่าโลหิตวิทยา ปริมาณเชื้อจุลินทรีย์ในไส้ตัน และสัณฐานวิทยาของลำไส้เล็กในไก่เนื้อ โดยทำการสุ่มลูกไก่เนื้อพันธุ์ Ross 308 อายุ 1 วัน จำนวน 500 ตัว แบ่งเป็น 5 กลุ่มอาหารทดลอง แต่ละกลุ่มมี 10 ซ้ำ ซ้ำละ 10 ตัว ประกอบด้วย อาหารที่ไม่มียาปฏิชีวนะเป็นกลุ่มควบคุมเชิงลบ (Negative control; NC) อาหารพื้นฐานเสริมด้วยยาปฏิชีวนะกระตุ้นการเจริญเติบโตเป็นกลุ่มควบคุมเชิงบวก (Positive control; PC) และ อาหาร NC ที่เสริมด้วย SCGE ที่ระดับ 0.5, 1.0 และ 2.0 ก./กก. อาหาร ตามลำดับ ผลการศึกษาชี้ให้เห็นว่า กลุ่ม SCGE และ PC มีน้ำหนักตัวสุดท้ายและอัตราการเจริญเติบโต (Average Daily Gain; ADG) สูงกว่ากลุ่ม NC (P<0.05) ทั้งนี้กลุ่ม SCGE ทุกกลุ่มมีประสิทธิภาพการเปลี่ยนอาหารเป็นน้ำหนักตัว (Feed Conversion Ratio; FCR) ดีกว่ากลุ่ม PC และ NC (P<0.05) ปริมาณเชื้อ Lactobacillus spp. ในไส้ตันของกลุ่ม SCGE1.0 และ SCGE2.0 มากกว่า (P<0.05) กลุ่ม PC โดยกลุ่ม NC และ SCGE0.5 มีค่าน้อยที่สุด (P<0.05) กิจกรรมของเอนไซม์ Alanine aminotransferase (ALT) ของกลุ่ม SCGE0.5 SCGE1.0 และ SCGE2.0 มีค่าต่ำกว่ากลุ่ม NC (P<0.05) ส่วนของ Aspartate transaminase (AST) ของ SCGE2.0 มีค่าน้อยที่สุด (P<0.05) ค่าความสูงของวิลไลและความลึกของคริปท์ของลำไส้เล็กส่วนกลางของกลุ่ม SCGE มากกว่า กลุ่ม NC และ PC ดังนั้น การเสริม SCGE ที่ระดับ 2.0 ก./กก. ช่วยปรับปรุงน้ำหนักสุดท้าย ADG FCR และสมดุลของเชื้อในไส้ตันได้ จึงถือว่ามีศักยภาพในการใช้ทดแทนยาปฏิชีวนะในอาหารไก่เนื้อได้
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