Effect of Active Immunization against Somatostatin Hormone on Growth and Body Fat Quantity in Native Chickens
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Abstract
This research was conducted to assess the immuno-neutralization against somatostatin (SRIF) hormone for improvement of growth performance and body fat content in native chickens. The immunogen was prepared by conjugation between the SRIF and hemocyanin from marine crab (Scylla serrata Rathun) (SRIF- partial purified hemocyanin, SRIF-PHMCN). Twenty native chickens at 8 weeks old were allocated into 2 groups, 10 each for control and treatment. Chickens in treatment group were immunized with 40 mg SRIF-pHMCN by subcutaneous injection at 3 points along the midline at the back of the body at 8, 10, 14 and 18 week of ages. Parameters of the experiment were body weight (BW), average daily gain (ADG), feed conversion ratio (FCR), shank length, breast width, weight of hearts, livers, kidneys, pancreases, spleens and abdominal fat. The results showed that there were tendencies of improvement in the BW, ADG, FCR and shank length (p>0.05). Beast width of the birds in the treatment group at 12, 14, 16 and 18 weeks were, respectively, 7.9%, 9.3%, 11.4% and 8.7% larger than the control group (p<0.05). For visceral organs, there were no significant difference (p>0.05) in weight of hearts, livers, kidneys, pancreases, and spleens. But female chickens in treatment group at 20 weeks decreased in abdominal fat to 85% in comparison to female birds in the control group (p<0.05). In conclusion, actively immunization against somatostatin improved breast muscle growth and largely diminished abdominal fat content in native chickens.
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