Conception Rate in Dairy Cows Receiving a First or Repeatedly Used Controlled Internal Drug Release Devices in Timed Artificial Insemination Protocol

Main Article Content

Molarat Sangkate
Punnawut Yama
Narongrit Jaipolsaen
Tossapol Moonmanee
Siwat Sangsritavong

Abstract

      Controlled internal drug release (CIDR) devices for releasing progesterone have been used for reproductive management in dairy cattle. To minimize the cost, the devices can be reused upon disinfection after being used for 7-8 days. Therefore, this research aims) is to compare the conception rate of dairy cows after the first, second, and third use of CIDR devices timed following artificial insemination (TAI) protocol. A total of 783 cows received short-term hormonal protocol (9.5 days) by inserting CIDR for 7 days. At the initiation of the TAI protocol, cows were randomly assigned into three groups, (1st CIDR; n = 312), (2nd CIDR; n = 233), and (3rd CIDR; n = 238). Moreover, in each CIDR group, cows were subdivided into two types (primiparous and multiparous cows). Cows in all groups were inseminated on day 9.5 of the TAI protocol. Diagnosis of pregnancy was performed using ultrasound on days 30 and 60 after insemination. From the results, the 1st, 2nd, and 3rd used CIDR devices did not significantly change the conception rates on days 30 (28.8% vs. 25.3% vs. 28.2%, respectively) and 60 (26.9% vs. 24.5% vs. 27.7%, respectively) post-TAI in dairy cows (P > 0.05). The embryonic loss did not differ among cows receiving the 1st, 2nd, and 3rd used CIDR devices (6.7% vs. 3.4% vs. 1.5%, respectively) (P > 0.05). For each CIDR group, parity (primiparous and multiparous) did not alter conception rates on days 30 and 60 post-TAI and embryonic loss in dairy cows (P > 0.05). Our findings indicate that the CIDR device could be used at least three times in the TAI protocol in primiparous and multiparous dairy cows.

Article Details

How to Cite
Sangkate, M., Yama, . P., Jaipolsaen, N., Moonmanee, T., & Sangsritavong, S. . (2024). Conception Rate in Dairy Cows Receiving a First or Repeatedly Used Controlled Internal Drug Release Devices in Timed Artificial Insemination Protocol. King Mongkut’s Agricultural Journal, 42(3), 276–280. https://doi.org/10.55003/kmaj.2024.11.22.001
Section
Research Articles

References

Cerri, R. L. A., Rutigliano, H. M., Bruno, R. G. S., & Santos, J. E. P. (2009). Progesterone concentration, follicular development and induction of cyclicity in dairy cows receiving intravaginal progesterone inserts. Animal Reproduction Science, 110(1-2), 56-70. https://doi.org/10.1016/j.anireprosci.2007.12.005.

Chacher, M. F. A., Çolak, A., & Hayirli, A. (2017). Efficacy of repeatedly used CIDR device in cattle reproduction: a metaanalysis review of progesterone concentration and conception rate. Turkish Journal of Veterinary and Animal Sciences, 41(5), 692-697. https://doi.org/10.3906/vet-1706-75.

Colazo, M. G., Kastelic, J. P., Whittaker, P. R., Gavaga, Q. A., Wilde, R., & Mapletoft, R. J. (2004). Fertility in beef cattle given a new or previously used CIDR insert and estradiol, with or without progesterone. Animal Reproduction Science, 81(1-2), 25-34. https://doi.org/10.1016/j.anireprosci.2003.09.003.

El-Tarabany, M. S. (2015). Effects of non-lactating period length on the subsequent calving ease and reproductive performance of Holstein, Brown Swiss and the crosses. Animal Reproduction Science, 158, 60–67. https://doi.org/10.1016/j.anirepro sci.2015.04.008.

El-Tarabany, M. S. (2016). The efficiency of new CIDR and once-used CIDR to synchronize ovulation in primiparous and multiparous Holstein cows. Animal Reproduction Science, 173(2016), 29-34. https://doi.org/10.1016/j.anireprosci.2016.08.006.

Galvão, K. N., Santos, J. E. P., Junchem, S. O., Cerri, R. L. A., Coscioni, A. C., & Villaseñor, M. (2004). Effect of addition of a progesterone intravaginal insert to a timed insemination protocol using estradiol cypionate on ovulation rate, pregnancy rate, and late embryonic loss in lactating dairy cows. Journal of Animal Science, 82(12), 3508-3517. https://doi.org/10.2527/2004. 82123508x.

Grohn, Y. T., & Rajala-Schultz, P. J. (2000). Epidemiology of reproductive performance in dairy cows. Animal Reproduction Science, 60–61, 605–614. https://doi.org/10.1016/s0378-4320(00)00085-3.

Mapletoft, R. J., Martínez, M. F., Colazo, M. G., & Kastelic, J. P. (2003). The use of controlled internal drug release devices for the regulation of bovine reproduction. Journal of Animal Science, 81(14 suppl 2), E28–E36. https://doi.org/10.2527/2003.811 4_suppl_2E28x.

Muth-Spurlock, A. M., Poole, D. H., & Whisnant, C. S. (2016). Comparison of pregnancy rates in beef cattle after a fixed time AI with once- or twice-used controlled internal drug release devices. Theriogenology, 85(2016), 447-451. https://doi.org/10.1016/ j.theriogenology.2015.09.019.

Rathbone, M. J., Runt, C. R., Ogle, C. R., Burggraaf, S., Macmillan, K. L., & Pickering, K. (2002). Development of an injection molded poly (e-caprolactone) intravaginal insert for the delivery of progesterone to cattle. Journal of Controlled Release, 85 (1-3), 61-71. https://doi.org/10.1016/S0168-3659(02)00272-9.

Sales, J. N. S., Carvalho, J. B. P., Crepaldi, G. A., Soares, J. G., Girotto, R. W., Maio, J. R. G., Souza, J. C., & Baruselli, P. S. (2015). Effect of circulating progesterone concentration during synchronization for fixed-time artificial insemination on ovulation and fertility in Bos indicus (Nelore) beef cows. Theriogenology, 83(6), 1093-1100. https://doi.org/10.1016/j.theriogenology. 2014.12.009

Steel, R. G. D., Torrie, J. H., & Dickey, D. (1997). Principles and Procedures of Statistics: A Biometrical Approach. McGraw-Hill Press.

Tjondronegoro, S., Williamson, P., Sawyer, G. J., & Atkinson, S. (1987). Effects of progesterone intravaginal devices on synchronization of estrus in postpartum dairy cows. Journal of Dairy Science, 70(10), 2162-2167. https://doi.org/10.3168/jds.S0022-0302(87)80269-2.

Zuluaga, J. F., & Williams, G. L. (2008). High-pressure steam sterilization of previously used CIDR inserts enhances the magnitude of the acute increase in circulating progesterone after insertion in cows. Animal Reproduction Science, 107(1-2), 30-33. https://doi.org/10.1016/j.anireprosci.2007.06.006.