Antioxidants and Inhibition of Skin Aging-related Enzyme Activities of the Flowers of Some Asteraceous Weeds
Article Sidebar
Main Article Content
Abstract
Protection and nourish the skin using natural extracts are alternate ways to solve skin problems.The natural product is one of the alternative ways to protect and nourish the skin/ or solve skin problems. The aims of this study were to analyze the quantity of phytochemicals (viz. total flavonoids and total phenolics) of ethanol flower extracts from fresh and dried samples of 6 weed species, including Bidens pilosa L., Sphagneticola trilobata (L.) Pruski, Eclipta prostrata (L.), Tridax procumbens L., Synedrella nodiflora (L.) Gaertn. and Vernonia cinerea Less. In addition, the extracts at a concentration of 100 µg/mL were investigated antioxidant properties (viz. DPPH and ABTS radical scavenging) and the inhibitory activities on skin aging-related enzymes
(viz. collagenase, elastase, hyaluronidase and tyrosinase). The results showed that ethanol extracts of dried samples from S. trilobata and B. pilosa contained high amount of total flavonoids and total phenolics. The extracts of dried flowers had better antioxidant properties on DPPH and ABTS scavenging reactions than other weed extracts. In the case of the performance of ethanol flower extracts from weeds, they showed a mild efficacies on inhibition of skin-aging related enzymes. Ethanol extracts of fresh sample from S. nodiflora presented inhibitory activities on collagenase, elastase, hyaluronidase and tyrosinase. However, identification of active compounds from ethanol flower extracts of S. trilobata, B. pilosa and S. nodiflora should be conducted.
Article Details
References
Abad, M.J., P. Bermejo, E. Carretero, C. Martinez-Acitores, B. Noguera and A. Villar. 1996. Antiinflammatory activity of some medicinal plant extracts from Venezuela. Journal of Ethnopharmcology 55(1): 63-68.
Abu-Orabi, S.T., M.A. Al-Qudah, N.R. Saleh, T.T. Bataineh, S.M. Obeidat, M.S. Al-Sheraideh, H.I. Al-Jaber, H.I. Tashtoush and J.N. Lahham. 2020. Antioxidant activity of crude extracts and essential oils from flower buds and leaves of Cistus creticus and Cistus salviifolius. Arabian Journal of Chemistry 13: 6256-6266.
Agustini, T.W., M. Suzery, D. Sutrisnanto, W.F. Ma’ruf and Hadiyanto. 2015. Comparative study of bioactive substances extracted from fresh and dried Spirulina sp. Procedia Environmental Sciences 23: 282-289.
Bernard, D., A.I. Kwabena, O.D. Osei, G.A. Daniel, S.A. Elom and A. Sandra. 2014. The effect of different drying methods on the phytochemicals and radical scavenging activity of Ceylon cinnamon (Cinnamomum zeylanicum) plant parts. European Journal of Medicinal Plants 4(11): 1324-1335.
Boskou, G., F.N. Salta, S. Chrysostomou, A. Mylona, A. Chiou and N.K. Andrikopoulos. 2006. Antioxidant capacity and phenolic profile of table olives from the Greek market. Food Chemistry 94(4): 558-564.
de Araújo, R., M. Lôbo, K. Trindade, D.F. Silva and N. Pereira. 2019. Fibroblast growth factors: a controlling mechanism of skin aging. Skin Pharmacology and Physiology 32: 275-282.
Deba, F., T.D. Xuan, M. Yasuda and S. Tawata. 2008. Chemical composition and antioxidant, antibacterial and antifungal activities of the essential oils from Bidens pilosa Linn. var. Radiata. Food Control 19: 346-352.
Demina, N.S. and S.V. Lysenko. 1996. Collagenolytic enzymes synthesized by microorganisms. Mikrobiologiia 65(3): 293-304.
Govindappa, M., S.S. Naga, M.N. Poojashri, T.S. Sadananda, C.P. Chandrappa, S. Gustavo, P. Sharanappa and N.V.A. Kumar. 2011. Antimicrobial, antioxidant and in vitro anti-inflammatory activity of ethanol extract and active phytochemical screening of Wedelia trilobata (L.) Hitchc. Journal of Medicinal Plants Research 5(24): 5718-5729.
Hasler, C.M. and J.B. Blumberg. 1999. Symposium on phytochemicals: biochemistry and physiology. Journal of Nutrition 129(3): 756S-757S.
Hassan, S. 2020. Positive aspects of weeds as herbal remedies and medicinal plants. Journal of Research in Weed Science 3(1): 57-70.
Hsu, C.F., H. Peng, C. Basle, J. Travas-Sejdic and P.A. Kilmartin. 2011. ABTS•+ scavenging activity of polypyrrole, polyaniline and poly(3,4-ethylenedioxythiophene). Polymer International 60(1): 69-77.
Jia, Z., M. Tang and J. Wu. 1999. The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. Food Chemistry 64(4): 555-559.
Kang, C.H., S.J. Rhie and Y.C. Kim. 2018. Antioxidant and skin anti-aging effects of marigold methanol extract. Toxicological Research 34(1): 31-39.
Kim, H.J., J. Yun, J. Lee, H. Hong, J. Jeong, E. Kim, Y.S. Bae and K.J. Lee. 2011. SUMO1 attenuates stress-induced ROS generation by inhibiting NADPH oxidase 2. Biochemical and Biophysical Research Communications 410(3): 555-562.
Kim, J.H., J.C. Byun, A.K.R. Bandi, C.G. Hyun and N.H. Lee. 2009. Compounds with elastase inhibition and free radical scavenging activities from Callistemon lanceolatus. Journal of Medicinal Plants Research 3(11): 914-920.
Lee, K.K., J.H. Kim, J.J. Choi and J.D. Choi. 1999. Inhibitory effects of 150 plant extracts on elastase activity, and their anti-inflammatory effects. International Journal of Cosmetic Science 21(2): 71-82.
Lee, W.C., C.C. Peng, C.H. Chang, S.H. Huang and C.C. Chyau. 2013. Extraction of antioxidant components from Bidens pilosa flowers and their uptake by human intestinal Caco-2 cells. Molecules 18(2): 1582-1601.
Meena, A.K., M.M. Rao, R.P. Meena, P. Panda and Renu. 2011. Pharmacological and phytochemical evidences for the plants of Wedelia genus - a review. Asian Journal of Pharmaceutical Reviews 1(1): 1-6.
Noda, K., M. Teerawatsakul, C. Prakongvongs and L. Chaiwiratnukul. 1994. Major Weeds in Thailand. 3rd ed. Mass & Medias Co., LTD., Bangkok. 164 p.
Pogrel, M.A., M.A. Low and R. Stern. 2003. Hyaluronan (hyaluronic acid) and its regulation in human saliva by hyaluronidase and its inhibitors. Journal of Oral Science 45(2): 85-91.
Sangmala, S. 2017. Introduction to dermatology. (Online). Available: https://meded.psu.ac.th /binla/ class05/388_573/intro_to_dematology /index.html (April 20, 2020). (in Thai)
Siddhuraju, P. and K. Becker. 2003. Antioxidant properties of various solvent extracts of total phenolic constituents from three different agroclimatic origins of drumstick tree (Moringa oleifera Lam.) leaves. Journal of Agricultural and Food Chemistry 51(8): 2144-2155.
Sonibare, M.A., O.T. Aremu and P.N. Okorie. 2016. Antioxidant and antimicrobial activities of solvent fractions of Vernonia cinerea (L.) Less leaf extract. African Health Science 16(2): 629-639.
Sowndhararajan, K., H. Cho, B. Yu and S. Kim. 2016. Comparison of essential oil compositions of fresh and dried fruits of Magnolia Kobus DC. Journal of Applied Pharmaceutical Science 6(4): 146-149.
Suwanagul, D. and R. Suwanketnikom. 2002. Weeds in Thailand. 1st ed. Kasetsart University Press, Bangkok. 440 p. (in Thai)
Tadtong, S., A. Viriyaroj, S. Vorarat, S. Nimkulrat and S. Suksamrarn. 2009. Antityrosinase and antibacterial activities of mangosteen pericarp extract. Journal of Health Research 23(2): 99-102.
Tamokou, J.D.D., A.T. Mbaveng and V. Kuete. 2017. Antimicrobial activities of African medicinal spices and vegetables. pp. 207-237. In: V. Kuete (ed.). Medicinal Spices and Vegetables from Africa: Therapeutic Potential Against Metabolic, Inflammatory, Infectious and Systemic Diseases. Academic Press, London.
Thring, T.S.A., P. Hili and D.P. Naughton. 2009. Anti-collagenase, anti-elastase and anti-oxidant activities of extracts from 21 plants. BMC Complementary and Alternative Medicine 9: 27, doi: 10.1186/1472-6882-9-27.
Udayashankar, A.C, M. Nandhini, S.B. Rajini and H.S. Prakash. 2019. Pharmacological significance of medicinal herb Eclipta alpa L.-a review. International Journal of Pharmaceutical Sciences and Research 10(8): 3592-3606.
Vaidya, B.N., T.A. Brearley and N. Joshee. 2014. Antioxidant capacity of fresh and dry leaf extracts of sixteen Scutellaria species. Journal of Medicinally Active Plants 2(3): 42-49.
Van Wart, H.E. and D.R. Steinbrink. 1981. A continuous spectrophotometric assay for Clostridium histolyticum collagenase. Analytical Biochemistry 113(2): 356-365.
Vierkötter, A. and J. Krutmann. 2012. Environmental influences on skin aging and ethnic-specific manifestations. Dermato-Endocrinology 4(3): 227-231.
Xuan, T.D. and T.D. Khanh. 2016. Chemistry and pharmacology of Bidens pilosa: an overview. Journal of Pharmaceutical Investigation 46(2): 91-132.
Zaidi, K.U., S.A. Ali and A.S. Ali. 2016. Effect of purified mushroom tyrosinase on melanin content and melanogenic protein expression. Biotechnology Research International 2016: Article ID 9706214, doi: 10.1155/2016/9706214.
Zungsontiporn, S., M. Thongros and T. Jongrukthai. 2015. Survey of weeds in vegetable in northeast and central region. (Online). Available: http://www.doa.go.th/research/ attachment.php?aid=851 (May 11, 2019). (in Thai)
